Evidence map›Paper›PMID 40094027›Full record

ArticleFrontiers in cardiovascular medicine2025

Characteristics of myocardial work during exercise stress echocardiography in healthy adults.

Liwei Huang, Luwei Ye, Hongmei Zhang, Qingfeng Zhang, Geqi Ding, Chunmei Li, Yan Deng, Lixue Yin, Yi Wang

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In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liwei Huang *Department of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Luwei Ye *Department of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Hongmei ZhangDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Qingfeng ZhangDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Geqi DingDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chunmei LiDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Yan DengDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lixue YinDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Yi WangDepartment of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-invasive myocardial work (MW) is a more precise parameter for evaluating left ventricular (LV) systolic function. However, studies examining sex-based differences in MW during exercise stress echocardiography (SE) in healthy individuals are scarce. Previous research has shown that global work efficiency (GWE) decreases following exercise. Objectives: To characterize sex-based differences in MW during exercise SE in healthy adults and to explore the factors influencing the decline in GWE post-exercise. Methods: The study enrolled 200 healthy adults, all of whom underwent echocardiographic assessments both at rest and immediately after completing a symptom-limited treadmill stress test. We measured LV volume, ejection fraction (EF), force, peak positive strain (PPS), global work index (GWI), global constructive work (GCW), global wasted work (GWW), and GWE at rest and post-exercise. Results: GWI, GCW, and GWW increased, while GWE decreased after exercise. There were no significant differences in any of the global MW parameters between sexes at rest (all Conclusion: Sex had a minimal effect on MW-based LV systolic function in healthy adults. GWE decreased post-exercise, and both PPS and force were independently associated with GWW. These findings suggest that higher contractility is achieved at the cost of increased wasted work, which subsequently leads to a decrease in mechanical efficiency.

Indexed as

exercise echocardiographyforcehealthy adultsmyocardial workpeak positive strain

Identifiers

PMID40094027
PMCPMC11906847

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