Evidence map›Paper›PMID 40093807›Full record

ArticleInternational journal of medical sciences2025

Metabolic syndrome is associated with gastroesophageal reflux disease in a large Taiwanese population study.

Wen-Hung Hsu, Jiun-Hung Geng, Pei-Yu Wu, Jiun-Chi Huang, Chao-Hung Kuo, Szu-Chia Chen

Abstract read
In one paragraph

Article in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Hung HsuDepartment of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 812, Taiwan.
Jiun-Hung GengDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Pei-Yu WuDepartment of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 812, Taiwan.
Jiun-Chi HuangDepartment of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 812, Taiwan.
Chao-Hung KuoDepartment of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 812, Taiwan.
Szu-Chia ChenDepartment of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 812, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) and metabolic syndrome (MetS) have emerged as prominent health issues in past decades. This study aimed to evaluate whether the presence of MetS and its constituent factors was associated with a higher likelihood of GERD in a large cohort of Taiwanese adults. MetS and its components were defined according to the modified National Cholesterol Education Program Expert Panel and Adult Treatment Panel III for Asians, and the presence of GERD was assessed using standardized interviews and questionnaires. Of 121,583 participants from the Taiwan biobank, 16,664 (13.7%) were diagnosed with GERD and 27,441 (22.6%) were diagnosed with MetS. After multivariable analysis, the participants with MetS (odds ratio [OR] = 1.079), abdominal obesity (OR = 1.094), hypertriglyceridemia (OR = 1.085), and low high-density lipoprotein cholesterol (OR = 1.073) (all

Indexed as

Gastroesophageal RefluxMetabolic SyndromeAdultAgedFemaleHumansHypertriglyceridemiaMaleMiddle AgedObesity, AbdominalRisk FactorsTaiwangastroesophageal reflux diseasemetabolic syndromeTaiwan Biobank

Identifiers

PMID40093807
PMCPMC11905277

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.