Evidence map›Paper›PMID 40093679›Full record

ArticleWorld journal of gastroenterology2025

Endoscopic full-thickness resection: A definitive solution for local complete resection of small rectal neuroendocrine neoplasms.

Xiao-Long Zhang, Yang-Yang Jiang, Ying-Ying Chang, Yu-Li Sun, Ying Zhou, Yao-Hui Wang, Xiao-Tan Dou, Hui-Min Guo, Ting-Sheng Ling

Abstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao-Long ZhangDigestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Yang-Yang JiangNanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Ying-Ying ChangNanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Yu-Li SunDigestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Ying ZhouDigestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Yao-Hui WangDepartment of Pathology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Xiao-Tan DouDepartment of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing 210008, Jiangsu Province, China.
Hui-Min GuoDepartment of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing 210008, Jiangsu Province, China.
Ting-Sheng LingDigestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China. chinalts2024@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, several endoscopic techniques have been used to improve the R0 resection rate of rectal neuroendocrine neoplasms (R-NENs). However, none of these methods can achieve 100% complete resection (CR), particularly in the vertical direction. Endoscopic full-thickness resection (EFTR) has proven to be an effective method for the treatment of submucosal tumors but is seldom utilized in the eradication of R-NENs.

aimTo review cases of R-NENs removed using EFTR and to evaluate the safety and efficacy of this technique.

methodsThis retrospective cohort study enrolled 160 patients with pathologically confirmed R-NENs, including 132 who underwent endoscopic submucosal dissection (ESD) and 28 who underwent EFTR. Lesions were categorized as < 1 cm, 1-2 cm, and > 2 cm in size. CR rate,

resultsEFTR achieved 100% CR rates for lesions < 1 cm and 1-2 cm, compared with 67.0% and 50.0%, respectively, in the ESD group.

conclusionEFTR has shown superior performance in the resection of small R-NENs compared with that of ESD.

Indexed as

Endoscopic Mucosal ResectionNeuroendocrine TumorsRectal NeoplasmsAdultAgedAged, 80 and overFemaleHumansIntestinal MucosaLength of StayMaleMiddle AgedOperative TimePostoperative ComplicationsRectumRetrospective StudiesComplete resectionEndoscopic full-thickness resectionEndoscopic submucosal dissectionEndoscopic techniqueRectal neuroendocrine neoplasms

Identifiers

PMID40093679
PMCPMC11886531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.