Evidence map›Paper›PMID 40093671›Full record

ArticleWorld journal of gastroenterology2025

Catching cancer signals in the blood: Innovative pathways for early esophageal cancer diagnosis.

Yue Zhao, Zhan Zhang, Jian-Hao Qiu, Rong-Yang Li, Zhen-Guo Sun

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yue ZhaoDepartment of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan 250063, Shandong Province, China.
Zhan ZhangDepartment of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan 250063, Shandong Province, China.
Jian-Hao QiuDepartment of Thoracic Surgery, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan 250063, Shandong Province, China.
Rong-Yang LiDepartment of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan 250063, Shandong Province, China.
Zhen-Guo SunDepartment of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan 250063, Shandong Province, China. sunzg@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, significant progress has been made in the application of DNA methylation for the early detection of esophageal cancer (EC). As an epigenetic modification, DNA methylation allows for noninvasive screening by detecting the methylation status of circulating tumor DNA. Studies have shown that the methylation of genes such as

Indexed as

Biomarkers, TumorCirculating Tumor DNADNA MethylationEarly Detection of CancerEsophageal NeoplasmsEpigenesis, GeneticHumansLiquid BiopsySeptinsBiomarkers, TumorCirculating Tumor DNASEPTIN9 protein, humanSeptinsCirculating tumor DNADNA methylationEarly detectionEsophageal cancerLiquid biopsyTreatment monitoring

Identifiers

PMID40093671
PMCPMC11886526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.