Evidence map›Paper›PMID 40093590›Full record

ReviewJPRAS open2025

Autologous nerve coverage in revision surgery for recurrent or persistent carpal tunnel syndrome: A systematic review and meta-analysis.

Tinatin Natroshvili, Dagmar Folkertsma, Marius A Kemler

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JPRAS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tinatin NatroshviliDepartment of Plastic Surgery, Martini Hospital, Van Swietenplein 1, 9728 NT Groningen, The Netherlands.
Dagmar FolkertsmaDepartment of Plastic Surgery, Martini Hospital, Van Swietenplein 1, 9728 NT Groningen, The Netherlands.
Marius A KemlerDepartment of Plastic Surgery, Martini Hospital, Van Swietenplein 1, 9728 NT Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initial carpal tunnel surgery fails in about 5% to 10% of cases, with revision rates from 0.3% to 7%. When repeated release is not feasible, autologous nerve coverage may be beneficial, although the optimal technique remains uncertain. The aim of this review was to systematically analyze postoperative outcomes of the different types of autologous nerve coverage techniques for recurrent or persistent carpal tunnel syndrome. A systematic review and meta-analysis of studies was performed in accordance with the PRISMA guidelines. Literature was searched in PubMed, Embase, CINAHL, and the Cochrane Central Register of Controlled Trials (CENTRAL). Among the 26 included studies, 8 different nerve coverage techniques were identified, but only 2 could be compared. Based on a random-effects model, meta-analysis showed that the hypothenar fat pad and the synovial flap both seem to be effective procedures, with more patients achieving complete relief of symptoms, satisfaction, and pain improvement in the hypothenar fat pad group.

Indexed as

Autologous nerve coverageCarpal tunnel syndromePersistentRecurrentRevision

Identifiers

PMID40093590
PMCPMC11908459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.