Evidence map›Paper›PMID 40093560›Full record

ReviewThe World Allergy Organization journal2025

WAO - ARIA consensus on chronic cough: Executive summary.

Philip W Rouadi, Samar A Idriss, Jean Bousquet, Mario Morais-Almeida, Cecilio R Azar, Mona Sulaiman Al-Ahmad, Anahí Yáñez, Maryam Ali Y Al-Nesf, Talal M Nsouli, Sami L Bahna and 31 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The World Allergy Organization journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Philip W RouadiDepartment of Otolaryngology, Dar Al Shifa Hospital, Hawally, Kuwait.
Samar A IdrissDepartment of Otolaryngology, Dar Al Shifa Hospital, Hawally, Kuwait.
Jean BousquetInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Mario Morais-AlmeidaAllergy Center, CUF Descobertas Hospital, Lisboa, Portugal.
Cecilio R AzarDepartment of Gastroenterology, American University of Beirut Medical Center (AUBMC), Beirut, Lebanon.
Mona Sulaiman Al-AhmadDepartment of Microbiology, College of Medicine, Kuwait University, Kuwait.
Anahí YáñezINAER - Investigaciones en Alergia y Enfermedades Respiratorias, Buenos Aires, Argentina.
Maryam Ali Y Al-NesfAllergy and Immunology Division, Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
Talal M NsouliInternational Cough Institute, Washington, DC, USA.
Sami L BahnaAllergy & Immunology Section, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
Eliane Abou-JaoudeInternational Cough Institute, Washington, DC, USA.
Fares H ZaitounAllergy, Asthma and Immunology Center, Beirut, Lebanon.
Usamah M HadiClinical Professor Department of Otolaryngology Head and Neck Surgery, American University of Beirut, Lebanon.
Glenis K ScaddingDepartment of ENT, RNENT Hospital and Division of Immunity and Infection, University College London, London, UK.
Peter K SmithClinical Medicine Griffith University, Southport, Qld, 4215, Australia.
René Maximiliano GómezFaculty of Health Sciences, Catholic University of Salta, Argentina.
Sandra N González-DíazUniversidad Autónoma de Nuevo León, Hospital Universitario and Facultad de Medicina, Monterrey, Nuevo León, Mexico.
Ludger KlimekCenter for Rhinology and Allergology, Wiesbaden, Germany.
Georges S JuvelekianVisiting Clinical Associate Professor of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Moussa A RiachyDepartment of Pulmonary and Critical Care, Hôtel-Dieu de France University Hospital, Beirut, Lebanon.
Giorgio Walter CanonicaHumanitas University & Personalized Medicine Asthma & Allergy Clinic-Humanitas Research Hospital-IRCCS-Milano, Italy.
David PedenUNC Center for Environmental Medicine, Asthma, and Lung Biology, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics UNC School of Medicine, USA.
Gary W K WongDepartment of Pediatrics, Chinese University of Hong Kong, Hong Kong, China.
James SublettDepartment of Pediatrics, Section of Allergy and Immunology, University of Louisville School of Medicine, 9800 Shelbyville Rd, Louisville, KY, USA.
Jonathan A BernsteinUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology, Cincinnati, OH, USA.
Lianglu WangDepartment of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, 100730, China.
Luciana Kase TannoUniversité Montpellier, Montpellier, France.
Manana ChikhladzeMedical Faculty at Akaki Tsereteli State University, National Institute of Allergy, Asthma & Clinical Immunology, KuTaisi, Tskaltubo, Georgia.
Michael LevinDivision of Paediatric Allergology, Department of Paediatrics, University of Cape Town, South Africa.
Yoon-Seok ChangDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
Bryan L MartinDepartment of Otolaryngology, Division of Allergy & Immunology, The Ohio State University, Columbus, OH, USA.
Luis CaraballoInstitute for Immunological Research, University of Cartagena, Cartagena de Indias, Colombia.
Adnan CustovicNational Heart and Lund Institute, Imperial College London, UK.
José Antonio Ortega-MartellHealth Science Institute, Autonomous University of Hidalgo, Mexico.
Olivia J Ly LesslarThe National Centre for Neuroimmunology and Emerging Disease, Griffith University, Southport, Qld, 4215, Australia.
Pedro Giavina-BianchiClinical Immunology and Allergy Division, University of Sao Paulo, Brazil.
Nikolaos PapadopoulosAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian, University of Athens, Athens, Greece.
Elham HossnyAin Shams University, Ain Shams University Children's Hospital, Cairo, Egypt.
Motohiro EbisawaClinical Research Center for Allergy and Rheumatology, NHO Sagamihara National Hospital, Sagamihara, Japan.
Alessandro FiocchiTranslational Pediatric Research Area, Allergic Diseases Research Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Holy See.
Ignacio J AnsoteguiDepartment of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute cough is a highly prevalent symptom in clinical practice. Chronic cough is a complex disease with significant impact on quality of life. The mechanistic pathways of chronic cough in cough-comorbid clinical phenotypes are elusive. Mounting evidence suggests presence of a hypersensitive cough reflex and implication of transient receptor potential channels and P2X receptors in cough neuronal pathways. Previously, the World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough published updated experimental and clinical data on chronic cough, in addition to a multidisciplinary care pathway approach to its management. The goal of this manuscript is to provide clinicians with a succinct summary of chronic cough pathophysiology, clinical phenotypes, and management strategies in both primary and cough specialty care. This executive summary is a primer for clinicians on chronic cough. Increasing awareness on the topic among primary care physicians will improve the outcome of management of patients with chronic cough.

Indexed as

Chronic coughGastroesophageal reflux diseaseHypersensitive cough reflexLower airway diseaseMultifactorial chronic coughNeuromodulatorsPrimary care physicianRefractory chronic coughUnexplained chronic coughUpper airway disease

Identifiers

PMID40093560
PMCPMC11903822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.