ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025
Comparative Evaluation of Bilateral Cleft Earlobe Rejuvenation with and without Calendula Officinalis 10% V/W- Randomised Control Trial.
Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- An Update of Phytotherapeutic Advances of Marigold (Plants (Basel, Switzerland) · 2025Review
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Abstract
Calendula officinalis has anti microbial and anti inflammatory property and its usage for wound healing is the need of the hour. The ultimate aim of our research study was to evaluate and compare bilateral earlobe rejuvenation with and without Calendula officinalis. The purpose of the study was to examine the impact of calendula on wound healing and its effect in the duration of wound healing. This randomised control trial was conducted on patients with bilateral earlobe cleft and were advised for the treatment of earlobe repair. The technique used for repair was Cross Stitching Approach modified with subcutaneus suturing. The randomization for the calendula application and sequence was generated randomly by computer generated random numbering. Calendula ointment was placed in a double blinded manner by blinding the principal investigator and the statistician. Calendula ointment was applied every 12 hourly on one ear lobe for a period of 7 days and petroleum jelly was placed on the contralateral earlobe. Scar assessment was done using the Stony Brook Scar Evaluation Scale (SBSE) on 15th day postoperatively. The wound healing after earlobe repair in 35 patients was compared after 24 h, 7 days, and 15 days using an unpaired t test in this randomized control trial. Statistical significance was defined as a P-value of less than 0.01. The repeated measures ANOVA test was used to compare mean scores at different time intervals in groups 1 and 2. The Bon Feronic test was used to compare the mean score in groups 1 and 2 at different time intervals. Statistical significance was defined as a p-value of less than 0.01. The comparison of mean score on day 1 the (p value = 0.525), day 7 was (p value = 0.324) and day 15 which was clinically significant (p value < 0.001). Calendula ointment was found to be beneficial in wound healing after cleft earlobe repair in this study. Calendula ointment has demonstrated potential benefits in treating wounds in scheduled surgery with no post-operative problems, according to the findings of this study. This study sets the landmark for the use of Calendula ointment in the treatment of cleft earlobe rejuvenation in Maxillofacial surgery.
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