Study of the Role of Narrow Band Imaging in Detection of Recurrent/ Residual Lesion in Post Chemo/Radiotherapy of Hypopharyngeal and Laryngeal Malignancies.

NBI as a screening tool to detect recurrent/residual lesions in Post CT/RT patients of Hypopharyngeal and Laryngeal malignancies. To evaluate the effectiveness of Narrow Band Imaging (NBI) in detecting residual or recurrent tumors in the larynx and hypopharynx of patients previously treated with radiotherapy or chemoradiotherapy. 30 patients previously treated by employing RT or CRT with curative intent for laryngeal and hypopharyngeal malignancies were enrolled in the study and were followed up for at least 3 visits that are 1-3months, 3-6 months, and above 6 months respectively with white light endoscopy/video laryngoscopy and transnasal flexible videoendoscopy with NBI mode. The sensitivity of VLS was 40% and specificity was 100%, while the positive and negative predictive values were 100% and 76% respectively. The sensitivity of NBI was 100% and specificity was 90%, while the positive and negative predictive values were 83% and 100% respectively. The accuracy of NBI was found to be 93.3%. The study showed that transnasal videoendoscopy with NBI is an excellent method for follow-up in patients with laryngeal and hypopharyngeal carcinomas treated with RT or CRT. NBI mode improves cancer detection and helps in precise biopsy.