Evidence map›Paper›PMID 40093478›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025

The role of Botulinum Toxin for the Management of post Parotidectomy Sialocele: A Randomized Controlled Trial.

Maryam Sheykhveisi, Ehsan Khaauthori, Leila Mashhadi, Habibollah Esmaily, Kamran Khazaeni

Erratum issuedAbstract read
In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Maryam SheykhveisiSinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ehsan KhaauthoriSinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Leila MashhadiDepartment of Anesthesiology and Intensive Care, Mashhad University of Medical Sciences, Mashhad, Iran.
Habibollah EsmailyDepartment of Epidemiology and Biostatistics, Mashhad University of Medical Sciences, Mashhad, Iran.
Kamran KhazaeniDepartment of Otorhinolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parotid fistula or Sialocele is a general consequence of a penetrating injury of parotid gland or parotidectomy surgery which may be caused serious complications. Studies show different approaches had various effects on management of sialocele complications after parotidectomy. The purpose of this study is to evaluate the effects of botulinum toxin (BTX) on total/ partial and partial superficial parotidectomy complications. Methods: Patients with benign parotid gland tumors were included in this bicentric, double-blind, parallel, randomized clinical trial from 2021 to 2023. One hundred subjects underwent parotidectomy with/ without BTX injection were randomly assigned into two groups including the intervention (BTX group) ( Results: Hematoma, infection, opening of the wound, warmth or swelling was not observed in either group. BTX group had significantly lower Postoperative drainage volume versus control group on both 24 and 48 h after surgery (23 vs. 19 mL, Conclusion: The study results demonstrated that botulinum toxin may be safe and effective therefore BTX injection in improving parotidectomy complications like sialocele was recommended.

Indexed as

Botulinum ToxinParotidectomySialocele

Identifiers

PMID40093478
PMCPMC11909307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.