ArticleWellcome open research2024
Acceptability trial of local Indonesian snack (SISTIK) enriched with chicken liver and eggshell powder as a potential food to increase micronutrient intakes among women of reproductive age.
Article in Wellcome open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04564222 (Double-Blind Cluster Randomized Controlled Trial of Chicken Liver and Eggshell Crackers in Mothers During Pregnancy and Lactation in a Disadvantaged Setting in Indonesia), which is not on this map. Cited by 2 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Double-Blind Cluster Randomized Controlled Trial of Chicken Liver and Eggshell Crackers in Mothers During Pregnancy and Lactation in a Disadvantaged Setting in Indonesia
Who cites it
2 citing papers in PubMed.
- Chicken liver and eggshell crackers are a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: a double-blind, cluster randomized controlled trial (SISTIK Growth Study).BMC pregnancy and childbirth · 2025Trial
- Chicken hepatic injury and food safety: From etiological drivers to pathogenic mechanisms.Poultry science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Background: Chronic micronutrient deficiencies in Indonesian women and young children contribute to poor foetal and infant growth. To address this, we formulated micronutrient-enriched crackers (MEC) incorporating nutrient-rich chicken liver, rich in iron, zinc, vitamin A, and B vitamins, along with powdered eggshells as a calcium source. Known locally as ' Methods: A single-blinded, two-phase acceptability trial involved 81 non-pregnant women aged 19-35 years in Ujung Berung Sub-district, Bandung City, Indonesia. In Phase 1, participants sampled both MEC and standard wheat crackers (SWC) in a test feeding session and rated each product using a 7-point cued facial response scale, evaluating colour, smell, flavour, and texture. In Phase 2, participants were randomly assigned to receive a 14-day home supply (75 g/day) of either MEC (n=41) or SWC (n=40). Adherence was determined by weighing unconsumed products. Data were analysed using mixed linear model for liking scores and a t-test for adherence. Results: MEC received favourable ratings, with no significant differences compared to SWC in liking scores for colour (MEC 4.5±1.2 vs. SWC 5.4±0.9), smell (MEC 4.9±1.5 vs. SWC 5.6±0.9), flavour (MEC 4.9±1.4 vs. SWC 5.6±0.9), and texture (MEC 5.4±1.0 vs. SWC 5.7±0.8); p-value > 0.05. Average daily consumption over 14 days was comparable between groups (MEC: 50.8±23.0 g vs. SWC: 51.0±20.0 g; mean difference: -0.2 g; 95% CI: -6.5 to 6.1; p-value = 0.802). Conclusions: MEC demonstrates reasonable acceptability and feasibility as a daily snack, supporting its potential as a dietary intervention to improve women's micronutrient intake and reduce infant stunting, especially among those women who found it appealing. Registration: ClinicalTrials.gov ( NCT04564222, 25
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