Evidence map›Paper›PMID 40093262›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Cardiorespiratory Fitness Modifies the Relationship Between Arterial Stiffness and Cerebral Blood Flow Independent of Physical Activity.

B M Breidenbach, I Driscoll, M P Glittenberg, A J Paulsen, S Fernandes-Taylor, T Naren, G S Roberts, T L Brach, M M Jarchow, L E Symanski and 9 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

B M BreidenbachORCID 0000-0001-6366-9818
I Driscoll
M P Glittenberg
A J Paulsen
S Fernandes-Taylor
T Naren
G S Roberts
T L Brach
M M Jarchow
L E Symanski
A Y Gaul
S R Lose
L A Rivera-Rivera
S C Johnson
S Asthana
B T Christian
D B Cook
O Wieben
O C Okonkwo

Funding

CSRD VA IK6 CX002369
6 · The paper itself

Abstract

introductionCentral arterial stiffness and cerebral blood flow (CBF) are inversely related. Poor cardiorespiratory fitness (CRF) and low physical activity (PA) are related to both higher arterial stiffness and lower CBF. The present study examined (i) whether CRF or PA moderate the relationship between arterial stiffness and CBF and (ii) whether the intensity or the type of PA need to be considered.

methodsParticipants (N=78, Mean

resultsThe association between aoPWV and CBF differed by fitness levels, with a negative relationship in the low fitness group and positive relationships in the average and high fitness groups (all DISCUSSION: Average or high fitness, meeting the PA guidelines, and more specifically, moderate intensity and exercise-related PA seem to attenuate the negative relationship between aoPWV on CBF.

Identifiers

PMID40093262
PMCPMC11908333

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.