In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors.
Marc TatarDepartment of Ecology, Evolution and Organismal Biology, and The Center for the Biology of Aging, Brown University, Providence, RI, USA.ORCID 0000-0003-3232-6884 Wenjing ZhengDepartment of Ecology, Evolution and Organismal Biology, and The Center for the Biology of Aging, Brown University, Providence, RI, USA.
Rochele YamamotoDepartment of Ecology, Evolution and Organismal Biology, and The Center for the Biology of Aging, Brown University, Providence, RI, USA.ORCID 0009-0008-2983-3061 Noelle Curtis-JosephDepartment of Ecology, Evolution and Organismal Biology, and The Center for the Biology of Aging, Brown University, Providence, RI, USA.ORCID 0000-0003-2183-9238 Shengxi LiState Key Laboratory of Common Mechanism Research for Major Disease, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lin WangState Key Laboratory of Common Mechanism Research for Major Disease, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Funding
Deciphering the crosstalk between methionine metabolism and methyltransferases in health and diseaseR35GM146869 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Andrey A Parkhitko · 2022 to 2026
$2.3MGenome wide association analysis with Drosophila to discover how metformin effects longevityR01AG069639 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2020 to 2024
$2.0MAging regulation by non-autonomous signaling from Drosophila gut enteroendocrine cellsR01AG059563 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2018 to 2022
$1.9MAge remodels kidney-adrenal-heart interorgan communicationU01AG086161 · NIA · BROWN UNIVERSITY · PI Rujun Gong, MARC TATAR · 2024 to 2026
$1.9MMethionine Cycle as a Mechanistic Hub for the Hallmarks of AgingR01AG082801 · NIA · BROWN UNIVERSITY · PI Andrey A Parkhitko, MARC TATAR · 2023 to 2026
$1.7MTyrosine degradation pathway in mitochondrial dysfunction and agingR03AG075651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PARKHITKO, ANDREY A · 2022 to 2023
$159kCombined targeting of synthetic lethal partners in RB1-deficient cellsR03CA286521 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PARKHITKO, ANDREY A · 2024 to 2025
$159kNCI NIH HHS R03 CA286521NIA NIH HHS R01 AG059563NIA NIH HHS R01 AG069639NIA NIH HHS R01 AG082801NIA NIH HHS R03 AG075651NIA NIH HHS U01 AG086161NIGMS NIH HHS R35 GM146869
6 · The paper itselfAbstract
Insulin/insulin growth factor signaling is a conserved pathway that regulates lifespan across many species. Multiple mechanisms are proposed for how this altered signaling slows aging. To elaborate these causes, we recently developed a series of
Indexed as
dInrDrosophilainsulin/IGF receptorinsulin/IGF signalingkinase insert domainlifespanmethionine metabolismmethionine restriction
Identifiers
PMID40093182
PMCPMC11908128
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