Evidence map›Paper›PMID 40093172›Full record

ArticlebioRxiv : the preprint server for biology2025

Biopsychosocial Correlates of Resting and Stress-Reactive Salivary GDF15: Preliminary Findings.

Cynthia C Liu, Caroline Trumpff, Qiuhan Huang, Robert-Paul Juster, Martin Picard

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cynthia C LiuDivision of Behavioral Medicine, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0001-8765-5576
Caroline TrumpffDivision of Behavioral Medicine, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Qiuhan HuangDivision of Behavioral Medicine, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0009-0002-4387-5854
Robert-Paul JusterDepartment of Psychiatry and Addiction, University of Montreal, Montreal, Quebec, Canada.
Martin PicardDivision of Behavioral Medicine, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.

Funding

Mitochondrial regulation of stress reactivity in humansR01MH122706 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PICARD, MARTIN · 2020 to 2024
$3.8M
Psychobiological regulation and molecular characterization of cell-free mitochondrial DNA in humansR01MH137190 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Martin Picard, Caroline Trumpff · 2024 to 2026
$2.4M
NIMH NIH HHS R01 MH122706NIMH NIH HHS R01 MH137190
6 · The paper itself

Abstract

Growth differentiation factor 15 (GDF15) is a biomarker of energetic stress related to aging, disease, and mitochondrial defects. We recently showed that GDF15 is quantifiable in saliva and acutely inducible by psychosocial stress. To date, the associations between GDF15 and biopsychosocial factors and individual characteristics remain unknown. Here, in a sample of healthy working adults (

Indexed as

metabokinemitochondriapsychobiologypsychophysiologysex/genderstress responseTrier Social Stress Test – TSST

Identifiers

PMID40093172
PMCPMC11908215

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.