Evidence map›Paper›PMID 40093165›Full record

ArticlebioRxiv : the preprint server for biology2025

Decoding neuronal wiring by joint inference of cell identity and synaptic connectivity.

Himanshu Pawankumar Gupta, Anthony W Azevedo, Yu-C-Hieh David Chen, Kristi Xing, Peter A Sims, Erdem Varol, Richard S Mann

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Himanshu Pawankumar GuptaZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.ORCID 0000-0002-1939-3022
Anthony W AzevedoDepartment of Neurobiology and Biophysics, University of Washington, WA, USA.
Yu-C-Hieh David ChenDepartment of Biology, New York University, New York, NY, USA.
Kristi XingBarnard College, Columbia University, New York, NY, USA.
Peter A SimsDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Erdem VarolDepartment of Computer Science & Engineering at Tandon School of Engineering, New York University, New York, NY, USA.
Richard S MannZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.ORCID 0000-0002-4749-2765

Funding

Project 4: Neural Basis of Behavioral SequencesU19NS104655 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI MURRAY, RICHARD M · 2017 to 2021
$14.6M
Development and Function of an Adult Locomotion Circuit in DrosophilaR01NS070644 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANN, RICHARD S · 2010 to 2024
$6.2M
Tools to broaden access to high-throughput functional connectomicsRF1MH117808 · NIMH · HARVARD MEDICAL SCHOOL · PI LEE, WEI-CHUNG ALLEN, MACRINA, THOMAS · 2019 to 2019
$4.3M
Dissecting circuit and cellular mechanisms for limb motor controlRF1NS128785 · NINDS · UNIVERSITY OF WASHINGTON · PI TUTHILL, JOHN · 2022 to 2022
$1.1M
Transcriptional basis of stereotyped neural architecturesR00MH128772 · NIMH · NEW YORK UNIVERSITY · PI Erdem Varol · 2024 to 2026
$734k
Molecular control of stochastic color vision circuit assemblyK99EY035757 · NEI · NEW YORK UNIVERSITY · PI CHEN, YU-CHIEH DAVID · 2024 to 2025
$309k
NEI NIH HHS K99 EY035757NIMH NIH HHS R00 MH128772NIMH NIH HHS RF1 MH117808NINDS NIH HHS R01 NS070644NINDS NIH HHS RF1 NS128785NINDS NIH HHS U19 NS104655
6 · The paper itself

Abstract

Animal behaviors are executed by motor neurons (MNs), which receive information from complex pre-motor neuron (preMN) circuits and output commands to muscles. How motor circuits are established during development remains an important unsolved problem in neuroscience. Here we focus on the development of the motor circuits that control the movements of the adult legs in

Identifiers

PMID40093165
PMCPMC11908227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.