Evidence map›Paper›PMID 40093135›Full record

ArticlebioRxiv : the preprint server for biology2024

Brain-wide projections of mouse dopaminergic zona incerta neurons.

Bianca S Bono, Kenichiro Negishi, Yasmina Dumiaty, Monica S Ponce, Titilayo C Akinbode, Kayla S Baker, C Duncan P Spencer, Elizabeth Mejia, Marina Guirguis, Alex J Hebert and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Bianca S BonoDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.ORCID 0000-0002-5078-9682
Kenichiro NegishiDepartment of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0001-8283-9202
Yasmina DumiatyDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.ORCID 0000-0003-1784-9361
Monica S PonceDepartment of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA.
Titilayo C AkinbodeDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.
Kayla S BakerDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.
C Duncan P SpencerDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.ORCID 0009-0008-5562-4861
Elizabeth MejiaDepartment of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA.
Marina GuirguisDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.
Alex J HebertDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.
Arshad M KhanDepartment of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0003-0254-3546
Melissa J CheeDepartment of Neuroscience, Carleton University, Ottawa, ON, K1S 5B6, Canada.ORCID 0000-0003-3815-9095

Funding

Interrogating brain circuits that control feeding caused by fasting or by cravingSC1GM127251 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI KHAN, ARSHAD M. · 2018 to 2021
$1.4M
NIGMS NIH HHS SC1 GM127251
6 · The paper itself

Abstract

The zona incerta (ZI) supports diverse behaviors including binge feeding, sleep/wake cycles, nociception, and hunting. This diversity of functions can be attributed to the heterogenous neurochemicals, cytoarchitecture, and efferent connections that characterize the ZI. The ZI is predominantly GABAergic, but we recently identified a subset of medial ZI GABA cells that co-express dopamine (DA), as marked by the enzyme tyrosine hydroxylase (TH). While the role of GABA within the ZI is well studied, little is understood about the function of ZI DA cells. To identify potential roles of ZI DA cells we mapped the efferent fiber projections from

Indexed as

AB_10013483AB_11177031AB_2201528AB_2315778AB_2340593axondopamineGABAHypothalamusmidbrainSCR_016477thalamustracing

Identifiers

PMID40093135
PMCPMC11908183

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.