Evidence map›Paper›PMID 40093100›Full record

ArticlebioRxiv : the preprint server for biology2025

Oxygen/glucose-deprivation causes long-term impairment of synaptic CaMKII movement.

Olivia R Buonarati, Nidia Quillinan, K Ulrich Bayer

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivia R BuonaratiDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Nidia QuillinanDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
K Ulrich BayerDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0003-0893-2200

Funding

Sex Steroids and Brain Outcome from Cardiac Arrest/Cardiopulmonary ResuscitationR01NS046072 · NINDS · UNIVERSITY OF COLORADO DENVER · PI HERSON, PACO S, QUILLINAN, NIDIA · 2002 to 2024
$7.0M
CaMKII substrate-selection in opposing forms of synaptic plasticityR01NS081248 · NINDS · UNIVERSITY OF COLORADO DENVER · PI K. Ulrich Bayer · 2013 to 2026
$4.9M
CaMKII nitrosylation in the age-related decline of synaptic plasticityR01AG067713 · NIA · UNIVERSITY OF COLORADO DENVER · PI BAYER, K. ULRICH · 2020 to 2024
$2.7M
CaMKII in global cerebral ischemiaR01NS080851 · NINDS · UNIVERSITY OF COLORADO DENVER · PI BAYER, K. ULRICH, HERSON, PACO S · 2013 to 2017
$2.1M
CaMKII in global cerebral ischemia: mechanisms and therapeutic interventionR01NS118786 · NINDS · UNIVERSITY OF COLORADO DENVER · PI BAYER, K. ULRICH, HERSON, PACO S · 2021 to 2025
$1.9M
A-beta/APP signaling impairs CaMKII-dependent synaptic plasticity after ischemic brain injuryF32AG066536 · NIA · UNIVERSITY OF COLORADO DENVER · PI ASFAHA, OLIVIA RUTH · 2020 to 2021
$106k
NIA NIH HHS F32 AG066536NIA NIH HHS R01 AG067713NINDS NIH HHS R01 NS046072NINDS NIH HHS R01 NS080851NINDS NIH HHS R01 NS081248NINDS NIH HHS R01 NS118786
6 · The paper itself

Abstract

Learning and memory are thought to require hippocampal long-term potentiation (LTP), a form of synaptic plasticity that is persistently impaired after cerebral ischemia and that requires movement of the Ca

Identifiers

PMID40093100
PMCPMC11908153

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.