Biocompatibility and antimicrobial properties of titanium and Zirconium-infused denture base resins.

Rajul Vivek, Sarita Aneja, Sneha Amit Rathi, Abha Kumari, Harsh Chansoriya, Shivakshi Chansoriya

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Article in Bioinformation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Rajul VivekDepartment of Prosthodontics & Crown and Bridge, Purvanchal Institute of Dental Sciences, Gorakhpur, Uttar Pradesh, India.

Sarita AnejaDepartment of Dentistry, Shri Guru Ram Rai Institute of Medical Sciences and Hospital, Shri Mahant Indiresh Hospital, Dehradun, Uttarakhand, India.

Sneha Amit RathiDepartment of Prosthodontics & Crown and Bridge, Dr HSRSM Dental College, Hingoli, Maharashtra, India.

Abha KumariDepartment of Pharmacology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.

Harsh ChansoriyaDepartment of Prosthodontics & Crown and Bridge, Government College of Dentistry, Indore, Madhya Pradesh, India.

Shivakshi ChansoriyaDepartment of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titanium (Ti) and zirconium (Zr) have gained attention for their promising properties in medical and dental applications, including their biocompatibility and antimicrobial effects. Denture base resins primarily made of polymethyl methacrylate (PMMA), often face issues such as microbial adhesion and limited bioactivity. Incorporating Ti and Zr into these resins could enhance their biological properties. This study investigates the biocompatibility and antimicrobial efficacy of Ti- and Zr-infused denture base resins compared to conventional PMMA resins. Three groups of denture base resins were prepared: Group A (PMMA control), Group B (PMMA + 5 wt% Ti) and Group C (PMMA + 5 wt% Zr). Biocompatibility was assessed by culturing human gingival fibroblasts (HGFs) on resin samples and performing an MTT assay to evaluate cell viability over 72 hours. Antimicrobial properties were tested against

Indexed as

antimicrobial propertiesbiocompatibilityCandida albicansdenture base resinspolymethyl methacrylateStreptococcus mutansTitaniumzirconium

Identifiers

PMID40092867

DOI10.6026/9732063002001345

PMCPMC11904144

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