Evidence map›Paper›PMID 40092839›Full record

ArticleBMJ neurology open2025

Higher-level gait disorders: a population-based study on prevalence, quality of life, depression and confidence in gait and balance.

Jenny Larsson, William Hansson, Hanna Israelsson Larsen, Lars-Owe D Koskinen, Anders Eklund, Jan Malm

Abstract read
In one paragraph

Article in BMJ neurology open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. COMPREHENSIVE ANALYSIS OF MURINE GAIT DURING SKELETAL MATURATION.bioRxiv : the preprint server for biology · 2026
    Article
  4. Crab Walk-Like Gait in CSF1R-Related Leukoencephalopathy.Movement disorders clinical practice · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jenny Larsson *Department of Clinical Sciences, Neuroscience, Umeå University, Umea, Sweden.ORCID 0000-0002-4423-9465
William Hansson *Department of Clinical Sciences, Neuroscience, Umeå University, Umea, Sweden.ORCID 0000-0001-5614-7157
Hanna Israelsson LarsenDepartment of Clinical Sciences, Neuroscience, Umeå University, Umea, Sweden.
Lars-Owe D KoskinenDepartment of Clinical Sciences, Neuroscience, Umeå University, Umea, Sweden.ORCID 0000-0003-3528-8502
Anders EklundDepartment of Diagnostics and Intervention, Biomedical Engineering and Radiation Physics, Umeå University, Umea, Sweden.ORCID 0000-0002-2031-722X
Jan MalmDepartment of Clinical Sciences, Neuroscience, Umeå University, Umea, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Higher-level gait disorders (HLGDs) are slow, unsteady neurological GDs in older people. GDs can reduce quality of life (QoL) and cause depression. This has not been investigated in HLGD even though some HLGD causes are treatable, potentially affecting associated problems. We aimed to investigate gait and balance confidence, depressive symptoms and QoL in HLGD. Methods: In a population (n=3769, 65-84y), 798 reported gait impairment (questionnaire) and were clinically examined together with 249 age- and sex-matched controls. Gait property groups were formed: 'HLGD', 'other neurological GD', 'non-neurological GD' or 'no GD'. Swedish Falls Efficacy Scale (FES(S)), Modified Gait Efficacy Scale (mGES), Euro Quality of Life 5-Dimension 5-Level index, Euro Quality of Life Visual Analogue Scale (EQ VAS) and Geriatric Depression Scale-15 (GDS-15) were compared. Results: In the general population, 38% had GDs, of which 16% (n=87/561) were HLGDs, giving an HLGD prevalence of 5.8%; 26% (n=145/561) were other neurological GDs; and 59% (n=329/561) non-neurological GDs. HLGD had more depressive symptoms than non-neurological GD and no GD (GDS-15 HLGD, 3.9±3.4; non-neurological GD, 2.5±2.8; no GD, 1.4±2.0; p<0.05), lower EQ VAS (HLGD, 63±17; non-neurological GD, 71±18; no GD, 82±14; p<0.001), lower gait confidence (mGES HLGD, 60±22; non-neurological GD, 74±21; no GD, 90±13; p<0.001) and lower balance confidence (FES(S) HLGD, 93±32; non-neurological GD, 111±25; no GD, 124±13; p<0.001). Conclusions: HLGDs are common and associated with reduced QoL, reduced confidence in gait and balance, and depressive symptoms, emphasising awareness of mental health among older people with slow unsteady gait.

Indexed as

DEPRESSIONEPIDEMIOLOGYGAITMOVEMENT DISORDERSQUALITY OF LIFE

Identifiers

PMID40092839
PMCPMC11907029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.