Evidence map›Paper›PMID 40092796›Full record

ArticleACS omega2025

Discovery of Novel Pyrrolidine-Based Chalcones as Dual Inhibitors of α-Amylase and α-Glucosidase: Synthesis, Molecular Docking, ADMET Profiles, and Pharmacological Screening.

Bedriye Seda Kurşun Aktar, Yusuf Sıcak, Abdulkadir Bakırdöven, Gizem Tatar Yılmaz, Özlem Yılmaz, Ayşegül Karaküçük-İyidoğan, Demet Taşdemir, Ebru Sağlam, Emine Elçin Oruç-Emre

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Design,ACS omega · 2026
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bedriye Seda Kurşun AktarDepartment of Hair Care and Beauty Services, Yeşilyurt Vocational School, Malatya Turgut Özal University, Malatya 44090, Türkiye.ORCID https://orcid.org/0000-0002-1492-3266
Yusuf SıcakDepartment of Medicinal and Aromatic Plants, Köyceğiz Vocational School, Mugla Sitki Kocman University, Köyceğiz, Muğla 48000, Türkiye.ORCID https://orcid.org/0000-0003-2339-5837
Abdulkadir BakırdövenDepartment of Hair Care and Beauty Services, Yeşilyurt Vocational School, Malatya Turgut Özal University, Malatya 44090, Türkiye.
Gizem Tatar YılmazDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Türkiye.
Özlem YılmazDepartment of Chemistry, Faculty of Arts and Sciences, Tokat Gaziosmanpaşa University, Tokat 60250, Türkiye.
Ayşegül Karaküçük-İyidoğanDepartment of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep 27410, Türkiye.ORCID https://orcid.org/0000-0002-8088-6010
Demet TaşdemirDepartment of Medical Biochemistry, Faculty of Medicine, Gaziantep University, Gaziantep 27410, Türkiye.
Ebru SağlamRespiratory Diseases and Respiratory Surgery Research and Practice Center, Gaziantep University, Gaziantep 27410, Türkiye.
Emine Elçin Oruç-EmreDepartment of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep 27410, Türkiye.ORCID https://orcid.org/0000-0001-6840-9660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of chalcones containing a pyrrolidine moiety were synthesized to examine their

Identifiers

PMID40092796
PMCPMC11904715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.