Evidence map›Paper›PMID 40092756›Full record

ArticleACS omega2025

Mechanism for Peptide Bond Solvolysis in 98% w/w Concentrated Sulfuric Acid.

Janusz J Petkowski, Maxwell D Seager, William Bains, John H Grimes, Sara Seager

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Peptides adopt stable omega-loop structures in concentrated sulfuric acid.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Warm, water-depleted rocky exoplanets with surface ionic liquids: A proposed class for planetary habitability.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. The diversity of exoplanetary environments and the search for signs of life beyond Earth.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janusz J PetkowskiFaculty of Environmental Engineering, Wroclaw University of Science and Technology, 50-370Wroclaw,Poland.ORCID https://orcid.org/0000-0002-1921-4848
Maxwell D SeagerDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, Worcester, Massachusetts 01609, United States.
William BainsSchool of Physics & Astronomy, Cardiff University, 4 The Parade, Cardiff CF24 3AA, U.K.ORCID https://orcid.org/0000-0001-5503-3764
John H GrimesComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0003-1831-174X
Sara SeagerNanoplanet Consulting, Concord, Massachusetts 01742, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a mechanism for the solvolysis of the peptide bond in 98% (w/w) concentrated sulfuric acid based on the assessment of reactivity of four dipeptides at room temperature: l-alanyl-l-alanine (

Identifiers

PMID40092756
PMCPMC11904706

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.