Evidence map›Paper›PMID 40092744›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2025

The Impact of Comfort Eluting Agents and Replacement Frequency on Enhancing Contact Lens Performance.

Chau-Minh Phan, Alex Hui, Xinfeng Charlie Shi, Ying Zheng, Lakshman N Subbaraman, James Wu, Lyndon Jones

Abstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chau-Minh PhanCentre for Ocular Research & Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.ORCID 0000-0002-4401-9083
Alex HuiCentre for Ocular Research & Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.
Xinfeng Charlie ShiAlcon Research LLC, Fort Worth, TX, USA.ORCID 0000-0003-2987-9496
Ying ZhengAlcon Research LLC, Fort Worth, TX, USA.ORCID 0009-0009-5847-9820
Lakshman N SubbaramanAlcon Research LLC, Fort Worth, TX, USA.ORCID 0000-0002-7233-083X
James WuAlcon Research LLC, Fort Worth, TX, USA.ORCID 0000-0002-9540-7182
Lyndon JonesCentre for Ocular Research & Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.ORCID 0000-0002-7409-7349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review explores the development and clinical implications of soft contact lenses designed to elute comfort agents, emphasizing their role in enhancing user experience and ocular health. As discomfort remains one of the primary reasons for discontinuation of lens wear, this concept aims to address this challenge by gradually releasing these agents over their period of use. This review also explores the effectiveness, safety, and user satisfaction associated with frequent replacement schedules of these lenses. Clinical trials demonstrate that lenses with eluting comfort agents significantly reduce dryness and irritation, leading to improved wear-time and overall comfort. The findings suggest that frequent replacement not only enhances lens hygiene but also maximizes the therapeutic benefits of the eluted agents, promoting a healthier ocular environment. The implications for practice highlight a shift towards more patient-centered approaches in contact lens design and management, aiming to improve adherence and satisfaction among users. This research paves the way for future innovations in contact lens technology, focusing on personalized solutions that cater to individual comfort needs.

Indexed as

comfortcontact lensreplacement frequencywettability

Identifiers

PMID40092744
PMCPMC11910927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.