Evidence map›Paper›PMID 40092517›Full record

ArticleIJTLD open2025

Lung life HRQoL measure: psychometric properties and initial data in presumptive TB.

M G Anthony, G Hoddinott, C Purdy, V Luke, M Van Niekerk, A C Hesseling, M M van der Zalm

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

M G AnthonyDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
G HoddinottDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
C PurdyDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
V LukeDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
M Van NiekerkDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
A C HesselingDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
M M van der ZalmDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Funding

The long-term consequences of pulmonary tuberculosis and respiratory viruses on lung health in young South African childrenK43TW011028 · FIC · STELLENBOSCH UNIVERSITY · PI VAN DER ZALM, MARIEKE MARGREET · 2020 to 2024
$647k
FIC NIH HHS K43 TW011028
6 · The paper itself

Abstract

introductionHealth-related quality of life (HRQoL) data in young children with respiratory illnesses, including TB, are limited in low- and middle-income countries (LMICs). This study assessed the psychometric properties of the LuLi-Q measures in South African children with presumptive TB, focusing on children aged 0-5 years.

methodsIn a cross-sectional study within the UMOYA TB diagnostic study, HRQoL data were collected using the LuLi-Q-Tots (0-2 years) and LuLi-Q-Pres (3-5 years) measures. Analyses included descriptive statistics, item-total correlations, and Cronbach's alpha for reliability.

resultsAmong 160 children aged 0-5 years (50 aged 0-2 years, 110 aged 3-5 years), the LuLi-Q-Tots had minimal floor and ceiling effects (6.5%), effectively capturing HRQoL. The LuLi-Q-Pres showed substantial floor and ceiling effects (61%), but removing 29 items improved reliability (Cronbach's alpha: 0.96-0.97). Caregivers reported daily medication use (54%) and anxiety (72%) in the 0-2 group, while separation anxiety (65%) and jealousy (92%) were common in the 3-5 group.

conclusionThis study establishes a foundation for reliable HRQoL measures for young children with presumptive TB, guiding future research and patient-centred care in LMICs.

Indexed as

health-related quality of lifepaediatric TBpresumptive tuberculosispsychometric propertiesrespiratory illnesses

Identifiers

PMID40092517
PMCPMC11906021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.