Evidence map›Paper›PMID 40092421›Full record

ArticleOrthopaedic journal of sports medicine2025

Altered Joint Forces Found in Symptomatic Dysplastic Hips in Women During Sport-Specific Activities.

Molly C Shepherd, Rannon Huo, John C Clohisy, Jeffrey J Nepple, Michael D Harris

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Molly C ShepherdProgram in Physical Therapy, Washington University School of Medicine, St Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-8797-0848
Rannon HuoDepartment of Biomedical Engineering, Washington University in St Louis, St Louis, Missouri, USA.
John C ClohisyDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
Jeffrey J NeppleDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
Michael D HarrisProgram in Physical Therapy, Washington University School of Medicine, St Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-3475-819X

Funding

DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Longitudinal Biomechanics and Patient-Reported Outcomes after Periacetabular Osteotomy for Developmental Dysplasia of the HipR01AR081881 · NIAMS · WASHINGTON UNIVERSITY · PI Michael D Harris · 2023 to 2026
$1.8M
Building a data science workforce to improve the reproducibility of rehabilitation researchR25HD105583 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI David Nelson Kennedy, Sook-Lei Liew · 2022 to 2026
$812k
Muscle Geometry and its Influence on Function in Patients with Developmental Dysplasia of the HipK01AR072072 · NIAMS · WASHINGTON UNIVERSITY · PI HARRIS, MICHAEL D · 2018 to 2022
$554k
NIAMS NIH HHS K01 AR072072NIAMS NIH HHS R01 AR081881NICHD NIH HHS R25 HD105583NICHD NIH HHS T32 HD007434
6 · The paper itself

Abstract

Background: Many patients with developmental dysplasia of the hip (DDH) are young and highly active but often become limited by activity-induced pain. Characterizing how the abnormal bony geometry of DDH affects hip joint loading and multiplanar kinematics during sport-specific motions relevant to active patients may provide insight into injury mechanisms and inform optimal treatment options. Purpose/Hypothesis: The purpose of this study was to determine how hip joint loading and kinematics are altered in DDH during 2 common sport activities: running and multidirectional hop-cutting. It was hypothesized that superior and medial joint-reaction forces (JRFs) would be elevated during running and that medial JRFs would be elevated during hop-cutting when compared with controls. Study Design: Controlled laboratory study. Methods: Using patient-specific musculoskeletal modeling, both running and hop-cutting motions were analyzed for female patients with symptomatic DDH (DDH group) and female controls without hip disorders who were enrolled from October 2017 to August 2022. Hip joint angles, JRFs, and muscle forces were compared between the groups using 1-dimensional statistical parametric mapping. Results: Overall, 19 women in the DDH group and 19 female controls were included in the running analysis, and 13 women in the DDH group and 10 female controls were included in the hop-cutting analysis. During the running motion, medial hip JRFs and gluteal muscle forces were significantly elevated in the DDH group, while rectus femoris muscle forces were reduced. During the hop-cutting motion, medial hip JRFs, gluteus minimus, and gluteus medius muscle forces were elevated, while gluteus maximus forces were reduced in the DDH group. There were no significant group differences in hip joint angles for either activity. Conclusion: The lack of kinematic differences between women with symptomatic DDH and controls suggests that the JRF differences between groups stemmed from the abnormal joint geometry in the DDH group. These activities may have greater damaging potential than previously studied lower impact activities such as walking. Clinical Relevance: Better understanding of how loading varies from activity to activity can help patients with DDH, and clinicians understand the mechanistic causes of DDH-related hip pain and damage and plan appropriate intervention strategies.

Indexed as

cuttingdevelopmental dysplasia of the hipjoint-reaction forcesrunning

Identifiers

PMID40092421
PMCPMC11909653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.