ArticleJournal of clinical and experimental dentistry2025
Evaluation of Remineralization of White Spot Lesions with Quercetin Nanoparticles: An
Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: This study explored the synthesis of quercetin nanoparticles (QNPs) and evaluated the remineralization effect of QNPs on artificial white spot lesions on extracted human teeth. Material and Methods: QNPs were successfully synthesized, and their size was measured. Seventy-six extracted human molars were divided into 4 groups of n=19 to undergo a 10-day pH cycling protocol: 1000 ppm fluoride solution as aqueous NaF (group 1), 6.5% w/v quercetin microparticle solution (group 2), 4000 ppm QNP (group 3) and deionized water (group 4). Vickers microhardness tester, scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX) and atomic force microscopy (AFM) were used to measure the surface microhardness (SMH), Ca:P ratio and surface roughness (Ra), respectively. Results: After remineralization, the SMH values were significantly different among all the experimental groups ( Conclusions: It can be concluded from the results of this study that QNPs have similar remineralization potential to fluoride and are more effective than quercetin.
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