Evidence map›Paper›PMID 40092214›Full record

ArticleOpen veterinary journal2025

Effect of a feed supplement containing probiotics on fecal score and clinical parameters in dogs with chronic kidney disease and intestinal disorders: A pilot study.

Francesca Perondi, Ilaria Lippi, Natascia Bruni, Nicolò Lonigro, And Elisa Martello

Abstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca PerondiDepartment of Veterinary Science, University of Pisa, Pisa, Italy.
Ilaria LippiDepartment of Veterinary Science, University of Pisa, Pisa, Italy.
Natascia BruniCandioli Pharma S.r.l., Beinasco, Turin, Italy.
Nicolò LonigroDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
And Elisa MartelloDivision of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic kidney disease (CKD) in dogs is often accompanied by dysbiosis and abnormal gut microbiota composition, leading to gastrointestinal issues. Probiotics, including Aim: This pilot double-blinded, randomized controlled study aimed to assess the effects of a feed supplement containing these probiotics on clinical parameters and fecal consistency in dogs with CKD and intestinal disorders. Methods: Eight dogs with CKD were randomly assigned to receive the supplement (TRT, Results: The dogs in the TRT group exhibited improvements in fecal consistency and clinical parameters compared with the CTR group. Conclusion: The feed supplement under investigation seems beneficial for improving clinical conditions, gut health, and stool quality in dogs with CKD. Future studies with larger sample sizes and microbiota analyses are needed to gain a better understanding of the potential benefits of this supplement in managing CKD in dogs.

Indexed as

Dog DiseasesIntestinal DiseasesProbioticsRenal Insufficiency, ChronicAnimal FeedAnimalsDietary SupplementsDogsDouble-Blind MethodFecesFemaleGastrointestinal MicrobiomeMalePilot ProjectsBeneficial bacteriaCanineCKDGutRenal diseaseStool texture

Identifiers

PMID40092214
PMCPMC11910283

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.