Evidence map›Paper›PMID 40092212›Full record

ArticleOpen veterinary journal2025

Restoration of sperm quality in lead acetate-induced rats via treatment with

Wurlina Wurlina, Imam Mustofa, Dewa Ketut Meles, Aswin Rafif Khairullah, Adeyinka Oye Akintunde, Kadek Rachmawati, Niluh Suwasanti, Dewa Made Sucipta Putra, Sri Mulyati, Suzanita Utama and 6 more

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Protective potential ofOpen veterinary journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wurlina WurlinaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Imam MustofaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Dewa Ketut MelesDivision of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Aswin Rafif KhairullahResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Adeyinka Oye AkintundeDepartment of Agriculture and Industrial Technology, Babcock University, Ilishan Remo, Nigeria.
Kadek RachmawatiDivision of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Niluh SuwasantiDepartment of Clinical Pathology, Faculty of Medicine, Universitas Katolik Widya Mandala Surabaya, Surabaya, Indonesia.
Dewa Made Sucipta PutraDr. R. Soedjono Selong Hospital, East Lombok, Indonesia.
Sri MulyatiDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Suzanita UtamaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Ulul KhoiriyahProfession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Baich R Tyarraushananda DefvyantoProfession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Sila Faredy HerianaProfession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Katty Hendriana Priscilia RiwuDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Pendidikan Mandalika, Mataram, Indonesia.
Riza Zainuddin AhmadResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Audrey Gracelia RiwuFaculty of Medicine and Veterinary Medicine, Universitas Nusa Cendana, Kupang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lead intoxication triggers testicular toxicity via oxidative stress. Aim: This study aimed to explore the antioxidant potential of Methods: Twenty-five healthy rats were randomly and equally divided into five groups. Group C served as the negative control, whereas group C+ was exposed to lead acetate at 50-mg/kg body weight (BW)/day without MOLE. The T1, T2, and T3 groups were exposed to lead acetate at 50-mg/kg BW and concurrently received MOLE at doses of 200-, 316-, and 500-mg/kg BW/day, respectively, for 20 days. On the 21st day, all rats were euthanized for blood collection and testicle harvesting. Results: The result showed that exposure to lead acetate at 50-mg/kg BW/day in group C+ led to significant decreases ( Conclusion: MOLE effectively restores sperm quality in lead acetate-induced rats.

Indexed as

AntioxidantsMoringa oleiferaOrganometallic CompoundsPlant ExtractsSpermatozoaAnimalsMaleOxidative StressPlant LeavesRatsRats, WistarSemen AnalysisSperm MotilityAntioxidantslead acetateOrganometallic CompoundsPlant ExtractsLeydig cellsMalondialdehydeMembrane integrityReproductive healthSertoli cells

Identifiers

PMID40092212
PMCPMC11910306

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.