ArticleOpen veterinary journal2025
A preliminary study on physiological dynamism of various serum cardiac biomarkers in apparently healthy Sipli sheep of Pakistan.
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: For sheep in tropical/subtropical areas of the world, the reported mortality and morbidity rate regarding cardiomyopathies is quite low (1%-2%), yet it has been elucidated that many sheep slaughtered for meat purposes in Pakistan have enlarged hearts with underlying cardiac abnormalities. Aim: The present preliminary work is the first record of deducing normal reference intervals (RIs) for various serum cardiac biomarkers namely cardiac troponin I (cTnI), alanine transaminase (ALT), aspartate transaminase (AST), lactate dehydrogenase (LDH), creatine kinase-myocardial band (CK-MB), sodium (Na Methods: Apropos to aseptic blood collection and serum extraction, the attributes were deduced using commercially available kits. For the sake of analyses, the studied biomarkers were attributed as independent (Na Results: The RIs for cardiac serum biomarkers included in the present study were generally within the reference range provided for sheep with slight variations which might be attributed to physiological adaptation to harsh desert climate. The Na Conclusion: The results of the study present baseline data about these cardiac biomarkers which may be utilized for cardiac assessment of the sheep. It is recommended that the serum cardiac biomarkers ascertained in this study be studied in perspective to electrophysiology and ultrasonography of sheep heart for confirmed diagnosis/prognosis of cardiomyopathies.
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