Evidence map›Paper›PMID 40092182›Full record

ArticleOpen veterinary journal2025

Hospital-acquired catheter-associated urinary tract infections in critical care unit dogs with high rates of multidrug-resistant organisms.

Pojchanicha Aponrat, Osathee Detkalaya, Naruemon Phlongtong, Natnicha Eksatit, Suppada Kananub, Sarawan Kaewmongkol, Gunn Kaewmongkol

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Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Pojchanicha AponratInternal Medicine Unit, Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Osathee DetkalayaUrology Unit, Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Naruemon PhlongtongIntensive Care Unit, Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Natnicha EksatitCritical Care Medicine Unit, Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Suppada KananubDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Kasetsart University, Nakhon Pathom, Thailand.
Sarawan KaewmongkolFaculty of Veterinary Technology, Kasetsart University, Bangkok, Thailand.
Gunn KaewmongkolDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Urethral catheterization in the critical care unit often compromises the urinary tract's defense mechanisms of canine patients and potentially leads to hospital-acquired systemic infection. Clinical signs of hospital-acquired catheter-associated urinary tract infections (CAUTIs) are frequently absent in critical dogs. Aim: This study aimed to evaluate the correlation between urinalysis results and CAUTIs in critical care unit dogs and assess the impact of prior antibiotic treatment for underlying diseases and antibiotic-resistant bacteria. Methods: Twenty-eight dogs underwent urethral catheterization in the critical care unit of Kasetsart University Veterinary Teaching Hospital. Bacterial cultures and drug sensitivity tests were performed immediately after catheter placement (day 0), 3, and 7 and before removal. A positive urine culture was defined as ≥10 Results: No significant association was observed between urine cultures and urinalysis parameters, catheterization duration, breed, sex, neutering status, or age. Dogs pretreated with antibiotics exhibited CAUTI-free periods longer than previously reported. The Kaplan-Meier analysis showed that CAUTI-free probabilities were 92.8% at 3 days, declining to 60.7% by 7 days and 53.6% at 10 days. Alarmingly, 80% of the isolates (12/15) were multidrug-resistant organisms (MDRO) resistant to ≥3 antimicrobials. A high incidence of hospital-acquired CAUTIs was detected in 13 of 28 cases (46.4%). The dogs with CAUTIs stayed longer in the hospital than dogs without CAUTIs. Conclusion: A routine urinalysis is unreliable for predicting hospital-acquired CAUTIs. The high rate of MDRO among critical care dogs underscores the urgent need for judicious antibiotic use and the need for enhanced diagnostic methods in critical care settings. This study proposes that serial bacterial cultures combined with modified urine sediment examinations can better manage CAUTI detection and reduce the growth of MDROs in veterinary practice.

Indexed as

Catheter-Related InfectionsCross InfectionDog DiseasesDrug Resistance, Multiple, BacterialUrinary CatheterizationUrinary Tract InfectionsAnimalsAnti-Bacterial AgentsDogsFemaleHospitals, AnimalMaleUrinalysisAnti-Bacterial AgentsCanine patientsCatheter-associated urinary tract infectionCritical care unitHospital-acquired infectionUrinalysis

Identifiers

PMID40092182
PMCPMC11910284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.