Evidence map›Paper›PMID 40092081›Full record

ArticleAmerican journal of translational research2025

Hypermethylation of

Ailing Tu, Han Wu, Junjie Wang, Xinyang Hou, Minghua Wang, Meng Jiang, Xiumin Zhou

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ailing TuDepartment of Oncology, The First Affiliated Hospital of Soochow University Suzhou, Jiangsu, China.
Han WuDepartment of Biochemistry and Molecular Biology, Medical College, Soochow University Suzhou, Jiangsu, China.
Junjie WangDepartment of Biochemistry and Molecular Biology, Medical College, Soochow University Suzhou, Jiangsu, China.
Xinyang HouDepartment of Oncology, The First Affiliated Hospital of Soochow University Suzhou, Jiangsu, China.
Minghua WangDepartment of Biochemistry and Molecular Biology, Medical College, Soochow University Suzhou, Jiangsu, China.
Meng JiangDepartment of Oncology, The First Affiliated Hospital of Soochow University Suzhou, Jiangsu, China.
Xiumin ZhouDepartment of Oncology, The First Affiliated Hospital of Soochow University Suzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicroRNAs (miRNAs) play crucial roles in gene regulation, and their dysregulation is associated with various diseases, including cancer. Abnormal DNA methylation can alter gene expression and influence carcinogenesis. DNA methylation-based biomarkers are emerging as promising tools for early cancer diagnosis. This study aimed to investigate the role of

methodsTo achieve these objectives, we employed multi-sample MethylTarget technology to assess the methylation status of

resultsWe found that

conclusionHypermethylated

Indexed as

esophageal cancerMethylationmiR-129-2-3pPPP6C

Identifiers

PMID40092081
PMCPMC11909538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.