Evidence map›Paper›PMID 40091998›Full record

ArticleCureus2025

Neonatal Outcomes of Umbilical Cord Milking, Early Cord Clamping and Delayed Cord Clamping in Term Infants: A Randomised Controlled Trial.

Saifon Chawanpaiboon, Sunisa Nuanjeen, Thitiya Wayuphak, Geeranda Oncharoen, Arunee Phuengphaeng, Julaporn Pooliam

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Care of the Newborn and Cord During the Third Stage of Labour (Scientific Impact Paper No. 78).BJOG : an international journal of obstetrics and gynaecology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saifon ChawanpaiboonObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.
Sunisa NuanjeenObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.
Thitiya WayuphakObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.
Geeranda OncharoenObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.
Arunee PhuengphaengObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.
Julaporn PooliamObstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, THA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Optimal umbilical cord management at birth plays a crucial role in neonatal outcomes. While delayed cord clamping (DCC) has been associated with improved neonatal haematologic and hemodynamic status, early cord clamping (ECC) remains widely practised. Umbilical cord milking (UCM) has emerged as an alternative to DCC, potentially offering similar benefits while reducing the delay in neonatal resuscitation. This study aims to compare the effects of UCM, ECC, and DCC on neonatal outcomes in term infants born between 37 and 42 weeks of gestation. Methods A total of 225 pregnant women at 37-42 weeks' gestation were randomised into three groups: ECC, UCM, and DCC. Participants delivered by spontaneous vaginal delivery or caesarean section. Newborn haemoglobin, haematocrit, and micro-bilirubin levels were measured within 48 to 72 hours of birth. Maternal demographic data, blood loss volume, newborn Apgar scores at 1 and 5 minutes, neonatal complications, phototherapy requirements, and hospital stay durations were recorded. Baseline maternal characteristics, including antenatal visit counts and haematocrit levels at 32-34 weeks, were similar across groups. Results All three groups of pregnant women had no difference in baseline characteristics, number of antenatal visits and baseline haematocrit in the first visit and during 32-34 weeks of gestation. Haemoglobin and haematocrit between the DCC group (17.35 g/dl (2.18), 48.38% (5.76)), the UCM group (17.34 g/dl (2.09), 48.09% (5.70)) and in the ECC group (16.27 g/dl (1.95), 44.92% (5.080)) were different with statistically significant. Other results, including estimated blood loss, neonatal bilirubin, the requirement of phototherapy, blood exchange and neonatal complications, were not different among the three groups. Conclusion UCM and DCC improve neonatal haematologic parameters compared to ECC, with DCC showing the greatest benefits. However, DCC is associated with a higher risk of neonatal jaundice requiring phototherapy. UCM may serve as a viable alternative when immediate resuscitation is needed. Further research is required to refine optimal cord management strategies.

Indexed as

delayed cord clampingearly cord clampinghaematocrithaemoglobinmicro-bilirubinneonatal anaemiaumbilical cord milking

Identifiers

PMID40091998
PMCPMC11909419

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.