The Intriguing Blindness of Maria Theresia von Paradis and the Instructive Potential of Medical Biography.

Medical biography can introduce healthcare providers to clinically relevant subjects that are rarely encountered in traditional curricula. Maria Theresia von Paradis (1759-1824), the blind musical prodigy, faced doubt about her reputation because of a brief and questionable recovery of sight at the age of 18 years. Her story serves as an example of how extraordinary circumstances can be met with skepticism. Her miraculous return of vision 15 years after going blind was mediated and exploited in public demonstrations by Franz Mesmer, a promoter of the theory of animal magnetism. Maria's sight was lost a second time in 1778 just before Mesmer was driven from medical practice as a charlatan. Although the cause of her visual disability will never be known, it deviates from patterns of functional (hysterical) vision loss by its early age of onset, severity, and length of affliction. Paradis's early proficiency in playing musical instruments raises questions about savant syndrome, autism, feigned disability, and how the early loss of vision influences aspects of cognitive development.