ArticleCureus2025
Secondary Syphilis Presenting as Fulminant Hepatic Failure: A Case Report and Literature Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syphilis has afflicted humanity for centuries, and despite advances in prevention and treatment, its prevalence continues to rise. Certain forms of the disease remain underreported, contributing to an incomplete understanding of their presentations. This report details the case of a 20-year-old female who developed fulminant hepatic failure (FHF) associated with active secondary syphilis. Despite receiving penicillin treatment, she required a liver transplant. To raise awareness in the medical community, the authors also review similar cases from the literature. Notably, only two other reports of FHF linked to secondary syphilis in adults exist, highlighting the limited experience with this presentation. All three cases shared similar clinical features, and each patient met the criteria for placement on the liver transplant waiting list. Given the rising incidence and diverse manifestations of syphilis,
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Registered trials
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