Evidence map›Paper›PMID 40091938›Full record

ReviewCureus2025

Limitations of the Glasgow Coma Scale: Challenges and Considerations.

Christopher Andraos, Amman Siddiqi, James Brazdzionis, Javed Siddiqi

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher AndraosNeurological Surgery, Arrowhead Regional Medical Center, Colton, USA.
Amman SiddiqiResearch, Arrowhead Regional Medical Center, Colton, USA.
James BrazdzionisNeurosurgery, Riverside University Health System Medical Center, Moreno Valley, USA.
Javed SiddiqiNeurosurgery, Desert Regional Medical Center, Palm Springs, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a prominent cause of long-term disability and death in the United States. The Glasgow Coma Scale (GCS) plays a crucial role in managing TBI by providing a standardized method for assessing severity, monitoring progression, guiding treatment decisions, predicting outcomes, facilitating communication, and supporting research and quality improvement efforts. The scale offers a practical approach to assessing the impairment of consciousness in response to specific stimuli. However, to date, there is a paucity of literature discussing the limitations of the GCS. In this narrative review, we have analyzed seven studies published between 2009 and 2024 in hopes of highlighting some of the limitations, such as potential subjectivity in scoring, inability to assess certain brainstem reflexes, and the need for supplementary assessments for specific neurological conditions. After reviewing literature from the past 15 years, several limitations of the GCS become apparent, including its failure to incorporate brainstem reflexes with limitations arising due to sedation and intubation of the patient. Moreover, the GCS consists of three sub-scales that are summed and assumed to carry equal weight. This can result in a loss of information as it is possible to achieve identical GCS scores through various combinations. Awareness of the limitations of the GCS can be crucial for clinicians when making decisions in specific scenarios, while also encouraging consideration of potential improvements to the scale.

Indexed as

altered consciousnessglasgow coma scale (gcs)limitationsneuro-critical careneuro-surgeryscale compositiontraumatic brain injury (tbi)

Identifiers

PMID40091938
PMCPMC11908630

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.