Evidence map›Paper›PMID 40091745›Full record

ReviewHypertension (Dallas, Tex. : 1979)2025

Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.

Antonis A Armoundas, Faraz S Ahmad, Zachi I Attia, Dimitrios Doudesis, Rohan Khera, Konstantinos G Kyriakoulis, George S Stergiou, W H Wilson Tang

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. The role of artificial intelligence in hypertension management.Current opinion in nephrology and hypertension · 2026
    Review
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonis A ArmoundasCardiovascular Research Center, Massachusetts General Hospital and Broad Institute, Massachusetts Institute of Technology, Boston (A.A.A.).ORCID 0000-0001-5006-1547
Faraz S AhmadDivision of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL (F.S.A.).ORCID 0000-0002-2613-2541
Zachi I AttiaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (Z.I.A.).ORCID 0000-0002-9706-7900
Dimitrios DoudesisBritish Heart Foundation (BHF) Centre for Cardiovascular Science, University of Edinburgh, United Kingdom (D.D.).ORCID 0000-0001-6699-9476
Rohan KheraSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine (R.K.).ORCID 0000-0001-9467-6199
Konstantinos G KyriakoulisHypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Athens, Greece (K.G.K., G.S.S.).ORCID 0000-0001-8986-2704
George S StergiouHypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Athens, Greece (K.G.K., G.S.S.).ORCID 0000-0002-6132-0038
W H Wilson TangHeart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH (W.H.W.T.).ORCID 0000-0002-8335-735X

Funding

Addressing Health Disparities among Oklahoma Minority and Rural Communities through Clinical Research Education and Career DevelopmentR25MD011564 · NIMHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HOUCHEN, COURTNEY WAYNE, STAVRAKIS, STAVROS · 2017 to 2021
$2.7M
Deep learning enhanced detection and personalized monitoring of aortic stenosis - The DETECT-AS StudyR01AG089981 · NIA · YALE UNIVERSITY · PI Rohan Khera · 2024 to 2026
$2.4M
Translating Personalized Inference from Randomized Clinical Trials to Real-World Cardiovascular CareR01HL167858 · NHLBI · YALE UNIVERSITY · PI Rohan Khera · 2024 to 2026
$2.3M
Prevention and Treatment of Ventricular TachyarrhythmiasR01HL135335 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2020
$2.1M
Biomarker-guided optimization of transcutaneous vagal stimulation for atrial fibrillationR01HL161008 · NHLBI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Stavros Stavrakis · 2022 to 2026
$1.9M
Evaluating and Improving Utilization of Evidence-Based Medical Therapy in Patients with Heart Failure using Automated Tools in the Electronic Health RecordK23HL153775 · NHLBI · YALE UNIVERSITY · PI KHERA, ROHAN · 2021 to 2025
$918k
A Medical-Grade Smart-Phone Based Monitoring System (Supplement)R21EB026164 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2018 to 2020
$668k
Utility of Vagal Stimulation to Prevent the Onset of Ventricular ArrhythmiasR21HL137870 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2018
$468k
NHLBI NIH HHS K23 HL153775NHLBI NIH HHS R01 HL135335NHLBI NIH HHS R01 HL161008NHLBI NIH HHS R01 HL167858NHLBI NIH HHS R21 HL137870NIA NIH HHS R01 AG089981NIBIB NIH HHS R21 EB026164NIMHD NIH HHS R25 MD011564
6 · The paper itself

Abstract

Hypertension presents the largest modifiable public health challenge due to its high prevalence, its intimate relationship to cardiovascular diseases, and its complex pathogenesis and pathophysiology. Low awareness of blood pressure elevation and suboptimal hypertension diagnosis serve as the major hurdles in effective hypertension management. Advances in artificial intelligence in hypertension have permitted the integrative analysis of large data sets including omics, clinical (with novel sensor and wearable technologies), health-related, social, behavioral, and environmental sources, and hold transformative potential in achieving large-scale, data-driven approaches toward personalized diagnosis, treatment, and long-term management. However, although the emerging artificial intelligence science may advance the concept of precision hypertension in discovery, drug targeting and development, patient care, and management, its clinical adoption at scale today is lacking. Recognizing that clinical implementation of artificial intelligence-based solutions need evidence generation, this opinion statement examines a clinician-centric perspective of the state-of-art in using artificial intelligence in the management of hypertension and puts forward recommendations toward equitable precision hypertension care.

Indexed as

Artificial IntelligenceHypertensionAntihypertensive AgentsBlood PressureDisease ManagementHumansPrecision MedicineAntihypertensive Agentsartificial intelligenceblood pressurediagnosishypertensionpatient caretreatment

Identifiers

PMID40091745
PMCPMC12094096

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.