Evidence map›Paper›PMID 40091608›Full record

SynthesisJournal of the European Academy of Dermatology and Venereology : JEADV2026

Completed suicide in patients with skin disease: A systematic review and meta-analysis.

B Hrvatin Stancic, M A S Henning, N Eriksen, J Emilie Dornonville de la Cour, D M L Saunte, G B E Jemec

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of the European Academy of Dermatology and Venereology : JEADV, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Completed suicide in patients with skin disease: A systematic review and meta-analysis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Pooled it
  2. Review
  3. Suicide in patients with skin diseases: What to look out for?Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

B Hrvatin StancicDermatovenerology Department, University Medical Centre Ljubljana, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0001-5294-2225
M A S HenningPhoenix Research Center, Department of Dermatology and Allergy - Herlev and Gentofte Hospital, Copenhagen, Denmark.
N EriksenPhoenix Research Center, Department of Dermatology and Allergy - Herlev and Gentofte Hospital, Copenhagen, Denmark.
J Emilie Dornonville de la CourPhoenix Research Center, Department of Dermatology and Allergy - Herlev and Gentofte Hospital, Copenhagen, Denmark.
D M L SauntePhoenix Research Center, Department of Dermatology and Allergy - Herlev and Gentofte Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-7953-1047
G B E JemecFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral skin diseases have been associated with suicidality. However, the term 'suicidality' encompasses ideation, which weakens the conclusions. In contrast, the much stronger endpoint of completed suicide and skin disease remains ambiguous.

objectivesTo determine the risk of completed suicide in adult patients with skin diseases.

methodsThe Pubmed, Embase and PsycINFO databases were performed from inception up to June 2023. All original studies in English with a minimum of 10 adult patients that assessed the relationship between a skin disease and death by suicide, were eligible for inclusion.

resultsThirty-seven met the inclusion criteria. Owing to expected interstudy variations, a random effects model was used. A total of 13 skin diseases were identified: 17 population-based high-quality studies, 3,800,748 patients with skin disease, and 33,722,675+ controls were included in the meta-analysis (MA). Each skin disease was analysed separately. Psoriasis: six studies were included in the MA (odds ratio (OR): 1.42, 95% confidence interval (CI) (0.76; 2.68) and found no association. Dermatitis: five studies were included in the MA OR: 1.54, 95% CI (0.57; 4.17) and found no association. Melanoma: four studies were included in the MA, which found an association between melanoma and suicide Standardized mortality rate (SMR): 2.89, 95% CI (1.97; 3.81). Non-melanoma skin cancer: two studies were included in the MA; female patients showed an increased risk of completed suicide compared to the control group SMR: 1.30, 95% CI (1.12; 1.49). In patients with hidradenitis suppurativa, two studies were included in the MA OR: 2.86, 95% CI (1.56; 5.24) and showed a positive association between HS and completed suicide.

conclusionsSuicidality should be considered by physicians when treating dermatological disease, especially when treating patients with hidradenitis suppurativa and melanoma. The association between other skin diseases and completed suicide remains unclear, and further research is indicated.

Indexed as

Skin DiseasesSuicideSuicide, CompletedHumansPsoriasisSkin Neoplasms

Identifiers

PMID40091608
PMCPMC12723575

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.