Evidence map›Paper›PMID 40091547›Full record

ArticleTurkish archives of pediatrics2025

The Role of Artificial Intelligence for Early Diagnostic Tools of Autism Spectrum Disorder: A Systematic Review.

Purboyo Solek, Eka Nurfitri, Indra Sahril, Taufan Prasetya, Anggia Farrah Rizqiamuti, Burhan Burhan, Irma Rachmawati, Uni Gamayani, Kusnandi Rusmil, Lukman Ade Chandra and 2 more

Abstract read
In one paragraph

Article in Turkish archives of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Data-Driven Approaches for Autism Detection: A Comprehensive Review of Machine Learning Algorithms and Datasets.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Purboyo SolekDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0009-0000-0464-1233
Eka NurfitriDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0002-3819-116X
Indra SahrilDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0001-5965-7259
Taufan PrasetyaDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0002-3223-0527
Anggia Farrah RizqiamutiDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0001-7435-7182
Burhan BurhanDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0009-0004-4884-3805
Irma RachmawatiDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0009-0002-8072-4668
Uni GamayaniDepartment of Neurology, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0003-4707-8908
Kusnandi RusmilDepartment of Child Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0002-2173-317X
Lukman Ade ChandraDepartment of Pharmacology and Therapy, Gadjah Mada University Faculty of Medicine, Public Health and Nursing, Yogyakarta, Indonesia.ORCID 0009-0002-9320-6990
Irvan AfriandiDepartment of Public Health, Padjadjaran University Faculty of Medicine, Hasan Sadikin General Hospital, West Java, Indonesia.ORCID 0000-0002-5143-0524
Kevin GunawanAtma Jaya Catholic University of Indonesia Faculty of Medicine and Health Sciences, Jakarta, Indonesia.ORCID 0009-0007-8871-5893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in social communication and repetitive behaviors. This systematic review examines the application of artificial intelligence (AI) in diagnosing ASD, focusing on pediatric populations aged 0-18 years. Materials and methods: A systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. Inclusion criteria encompassed studies applying AI techniques for ASD diagnosis, primarily evaluated using metriclike accuracy. Non-English articles and studies not focusing on diagnostic applications were excluded. The literature search covered PubMed, ScienceDirect, CENTRAL, ProQuest, Web of Science, and Google Scholar up to November 9, 2024. Bias assessment was performed using the Joanna Briggs Institute checklist for critical appraisal. Results: The review included 25 studies. These studies explored AI-driven approaches that demonstrated high accuracy in classifying ASD using various data modalities, including visual (facial, home videos, eye-tracking), motor function, behavioral, microbiome, genetic, and neuroimaging data. Key findings highlight the efficacy of AI in analyzing complex datasets, identifying subtle ASD markers, and potentially enabling earlier intervention. The studies showed improved diagnostic accuracy, reduced assessment time, and enhanced predictive capabilities. Conclusion: The integration of AI technologies in ASD diagnosis presents a promising frontier for enhancing diagnostic accuracy, efficiency, and early detection. While these tools can increase accessibility to ASD screening in underserved areas, challenges related to data quality, privacy, ethics, and clinical integration remain. Future research should focus on applying diverse AI techniques to large populations for comparative analysis to develop more robust diagnostic models.

Identifiers

PMID40091547
PMCPMC11963361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.