Evidence map›Paper›PMID 40091480›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Silk Fibroin Nanoparticles for Enhanced Cuproptosis and Immunotherapy in Pancreatic Cancer Treatment.

Si Gao, Haodong Ge, Lili Gao, Ying Gao, Shuibin Tang, Yiming Li, Zhiqing Yuan, Wei Chen

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Spatiotemporal controlled release of YCM/CuJournal of nanobiotechnology · 2026
    Article
  5. Review
  6. Role of cuproptosis in digestive system tumors (Review).International journal of molecular medicine · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Copper Homeostasis, Emerging Central Players in Cancer Immunotherapy.Journal of cellular and molecular medicine · 2025
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Si GaoDepartment of Biliary-pancreatic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Haodong GeDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200020, China.
Lili GaoDepartment of Pathology, Xinhua Hospital, Affiliated to Medicine School of Shanghai Jiaotong University, Shanghai, 200092, China.
Ying GaoSchool of Stomatology, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, 010030, China.
Shuibin TangDepartment of Biliary-pancreatic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Yiming LiDepartment of Biliary-pancreatic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Zhiqing YuanDepartment of Biliary-pancreatic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Wei ChenDepartment of Biliary-pancreatic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.ORCID https://orcid.org/0000-0001-7107-6334

Funding

National Natural Science Foundation of China 81570545
6 · The paper itself

Abstract

Cuproptosis is a newly discovered copper ion-dependent programmed cell death. Elesclomol (ES) is a Cu

Indexed as

CopperFibroinsImmunotherapyNanoparticlesPancreatic NeoplasmsAnimalsCell Line, TumorHumansMiceTumor MicroenvironmentCopperFibroinscancer therapycuproptosiselesclomolsilk fibroinαPDL‐1

Identifiers

PMID40091480
PMCPMC12079484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.