Evidence map›Paper›PMID 40091435›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Developing Quorum Sensing-Based Collaborative Dynamic Control System in Halomonas TD01.

Yi-Na Lin, Yu-Xi Li, Ye Zheng, Yi-Hao Deng, Kai-Xuan Liu, Yue Gan, Hao Li, Jun Wang, Jia-Wen Peng, Rui-Zhe Deng and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. An Efficient COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Developing Quorum Sensing-Based Collaborative Dynamic Control System in Halomonas TD01.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yi-Na LinSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Yu-Xi LiSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Ye ZhengDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Yi-Hao DengSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Kai-Xuan LiuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Yue GanSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Hao LiSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Jun WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Jia-Wen PengSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Rui-Zhe DengDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Huai-Ming WangDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Hui WangDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Jian-Wen YeSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.ORCID https://orcid.org/0000-0003-2562-7283

Funding

Beijing Key Laboratory of Digital Stomatology Opening Fund PKUSS20230301China Postdoctoral Science Foundation 2022M721193Fundamental Research Funds for the Central University 2023ZYGXZR095Guangdong Provincial Department of Education Youth Innovative Talent Project 2024KQNCX003Guangdong S&T Program 2022B1111080006Industry-Academic Cooperation Foundation of Zhu Hai 2220004002580National Natural Science Foundation of China 32322003
6 · The paper itself

Abstract

Dynamic control exhibits increasing significance in microbial cell factory engineering by precisely manipulating gene expression over time and levels. However, the practical uses of most dynamic control tools still remain challenging because of poor scale-up robustness, especially for non-model chassis. Herein, a quorum sensing (QS)-based collaborative dynamic control system is constructed in Halomonas TD by regrouping two orthogonal quorum-sensing modules into two cell types, namely cell-A harboring cinR-luxI and cell-B harboring luxR-cinI together with sfGFP driven by P

Indexed as

HalomonasMetabolic EngineeringQuorum SensingBacterial ProteinsGene Expression Regulation, BacterialBacterial Proteinscell‐cell communicationdynamic controlHalomonashigh cell density inductionmetabolic engineeringquorum sensing

Identifiers

PMID40091435
PMCPMC12079531

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.