Evidence map›Paper›PMID 40091405›Full record

ArticleJournal of Parkinson's disease2025

Concordance between imaging and clinical based STN-DBS programming improves motor outcomes of directional stimulation in Parkinson's disease.

Leonardo Rigon, Francesco Bove, Alessandro Izzo, Nicola Montano, Livia Brusa, Rocco Cerroni, Alessandro De Biase, Lazzaro di Biase, Giorgio Quintino D'Alessandris, Danilo Genovese and 9 more

Abstract read
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. [Research progress on the neuromodulation targets in stroke rehabilitation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  3. Review
  4. Advanced Therapeutics in Parkinson's Disease: What's New?Current neurology and neuroscience reports · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Leonardo RigonDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-1986-3389
Francesco BoveDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-2959-6659
Alessandro IzzoNeurosurgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-6828-6768
Nicola MontanoNeurosurgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Livia BrusaNeurology Unit, S. Eugenio Hospital, Rome, Italy.
Rocco CerroniDepartment of System Medicine, UOSD Parkinson, University of Rome Tor Vergata, Rome, Italy.
Alessandro De BiaseDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0003-2419-1668
Lazzaro di BiaseOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.ORCID 0000-0001-8753-757X
Giorgio Quintino D'AlessandrisNeurosurgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-2953-9291
Danilo GenoveseDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-7603-5758
Pasquale Maria PecoraroOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.ORCID 0000-0001-6186-8020
Antonella PeppeIRCCS Santa Lucia Foundation, Rome, Italy.
Marina RizzoNeurology Unit, Azienda Ospedaliera Ospedali Riuniti Villa Sofia e Cervello, Palermo, Italy.
Alessandro StefaniDepartment of System Medicine, UOSD Parkinson, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-1806-8922
Antonio SuppaDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-9903-5550
Anna Rita BentivoglioDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-9663-095X
Paolo CalabresiDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0003-0326-5509
Carla PianoDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0003-0265-7666
Lazio DBS Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAdvances in STN-DBS technology, among which directional stimulation, improved Parkinson's disease (PD) treatment efficacy, while increasing the clinical programming complexity. Lead localization software may aid the stimulation contact selection process.ObjectiveWe aimed to assess the concordance between imaging-suggested (IGP) and conventional-programming (CP) selected stimulation contacts one year after surgery and its impact on motor outcomes.MethodsSixty-four PD patients with bilateral STN-DBS were enrolled. Lead localization was reconstructed with Brainlab

Indexed as

Deep Brain StimulationOutcome Assessment, Health CareParkinson DiseaseSubthalamic NucleusAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedTreatment Outcomedeep brain stimulationimaging-guided programminglead placement visualizationParkinson's diseasesubthalamic nucleus

Identifiers

PMID40091405
PMCPMC13347424

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.