Evidence map›Paper›PMID 40091387›Full record

ArticleScience progress

Exploring the predictive value of complete blood count inflammatory parameters in early pregnancy for missed abortion.

Lingna Huang, Jiaran Wang, Lebin Yan, Jingjing Wang, Xiumei Xiong

Abstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lingna HuangDepartment of Gynecology and Obstetrics, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.ORCID 0000-0002-7402-5839
Jiaran WangSchool of Basic Medicine Sciences, Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0004-7469-1526
Lebin YanSchool of Basic Medicine Sciences, Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0006-2457-879X
Jingjing WangSchool of Basic Medicine Sciences, Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0009-7418-0140
Xiumei XiongDepartment of Gynecology and Obstetrics, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0006-9220-516X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionThe aim of this study was to assess the potential role of complete blood count (CBC) inflammatory parameters in the diagnosis and management of missed abortions during early pregnancy through the analysis of their values.MethodsThe case group for our study comprised 500 instances of missed abortions at Fujian Provincial Maternal and Child Health Hospital from May 2023 to May 2024, whereas the control group consisted of 500 healthy women who did not experience delivery-related complications during this timeframe. We utilized SPSS version 25 software to conduct a retrospective analysis of factors, including age, BMI, gravidity, parity, neutrophil count, lymphocyte count, platelet count, mean platelet volume, platelet distribution width, and prothrombin time.ResultsThe age and gravidity of patients in the missed abortion group were higher than those in the normal pregnancy group, with a statistically significant difference. There were no significant differences in the platelet count, mean platelet volume, platelet distribution width, neutrophil count, or prothrombin time between the two groups. But the lymphocyte count was significantly lower in the missed abortion pregnancies. The area under the ROC curve for the lymphocyte count was 0.654, indicating its diagnostic value.ConclusionAlthough the lymphocyte count can offer some predictive value in detecting missed abortion, its diagnostic accuracy is limited. Other inflammatory parameters don't yield any predictive information regarding miscarriage retention.

Indexed as

Abortion, MissedPregnancy Trimester, FirstAdultFemaleHumansLymphocyte CountPregnancyRetrospective StudiesYoung Adultcomplete blood countlymphocyte countMissed abortionneutrophil countplatelet distribution width

Identifiers

PMID40091387
PMCPMC11912159

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.