Evidence map›Paper›PMID 40091320›Full record

ArticleJournal of microscopy2025

Model-based aberration corrected microscopy inside a glass tube.

Daniël W S Cox, Tom Knop, Ivo M Vellekoop

Abstract read
In one paragraph

Article in Journal of microscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniël W S CoxBiomedical Photonic Imaging Group, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.ORCID https://orcid.org/0009-0007-5304-345X
Tom KnopBiomedical Photonic Imaging Group, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Ivo M VellekoopBiomedical Photonic Imaging Group, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.

Funding

H2020 European Research Council 678919
6 · The paper itself

Abstract

Microscope objectives achieve near diffraction-limited performance only when used under the conditions they are designed for. In nonstandard geometries, such as thick cover slips or curved surfaces, severe aberrations arise, inevitably impairing high-resolution imaging. Correcting such large aberrations using standard adaptive optics can be challenging: existing solutions are either not suited for strong aberrations, or require extensive feedback measurements, consequently taking a significant portion of the photon budget. We demonstrate that it is possible to precompute the corrections needed for high-resolution imaging inside a glass tube based on a priori information only. Our ray-tracing-based method achieved over an order of magnitude increase in image contrast without the need for a feedback signal.

Indexed as

2PEFaberration correctiona prioridigital twinfluorescencelaser scanninglumenmicroscopymodel basednonlinearorgan‐on‐a‐chipray tracingspatial light modulatortubetwo‐photonwavefront shaping

Identifiers

PMID40091320
PMCPMC12068014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.