Evidence map›Paper›PMID 40090784›Full record

Trial reportThe journal of prevention of Alzheimer's disease2025

Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction.

Sylvie Belleville, Nicole D Anderson, Louis Bherer, Richard Camicioli, Julie Carrier, Senny Chan, Marc Cuesta, Thien Thanh Dang-Vu, Emily Dwosh, Alexandra J Fiocco and 24 more

2 registry-linked trialsAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journal of prevention of Alzheimer's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05167045 completednot on this map

A Pilot Study for the Brain Health Support Program (BHSP) Intervention of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia

TypeobservationalSponsorBaycrestRan2021 to 2022Enrolled20ConditionsDementia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Pre-dementiaArmsBrain Health PRO
NCT05347966 nacompletednot on this map

The Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia: Brain Health Support Program Intervention

TypeinterventionalSponsorBaycrestRan2022 to 2024Enrolled354ConditionsDementia Prevention, Mild Cognitive Impairment, Subjective Cognitive Impairment, Cognitive ChangeArmsBrain Health PRO
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Sylvie BellevilleCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada; Département de psychologie, Université de Montréal, Montréal, Québec, Canada. Electronic address: sylvie.belleville@umontreal.ca.
Nicole D AndersonRotman Research Institute, Baycrest Academy for Research & Education, Toronto, Ontario, Canada; Departments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Louis BhererCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada; Département de médecine, Université de Montréal, Montréal, Québec, Canada; Montreal Heart Institute, Montréal, Québec, Canada.
Richard CamicioliDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute, Edmonton, Alberta, Canada.
Julie CarrierDépartement de psychologie, Université de Montréal, Montréal, Québec, Canada; Center for Advanced Research in Sleep Medicine (CARSM), Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada.
Senny ChanDepartments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Marc CuestaCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada.
Thien Thanh Dang-VuCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada; Department of Health, Kinesiology and Applied Physiology, Concordia University, Montréal, Québec, Canada.
Emily DwoshDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Alexandra J FioccoInstitute for Stress and Wellbeing Research, Department of Psychology, Toronto, Canada.
Guylaine FerlandMontreal Heart Institute, Montréal, Québec, Canada; Département de nutrition, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada.
Brigitte GilbertClinique Bien Vieillir, Montréal, Québec, Canada.
Elaine HarrisCo-president of Citizen Advisory Group, Canada.
Inbal ItzhakLady Davis Institute for Medical Research, Montréal, Québec, Canada.
Pamela JarrettFaculty of Medicine, Department of Internal Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Geriatric Medicine, Horizon Health Network, Saint John, New Brunswick, Canada.
Mohamed Abdelhafid KadriCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada.
Danielle LaurinCentre d'excellence sur le vieillissement de Québec, CIUSSS de la Capitale-Nationale, INAF, Université Laval, Québec, Canada.
Teresa Liu-AmbroseDjavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, Canada; Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Chris A McGibbonFaculty of Kinesiology and Institute of Biomedical Engineering, University of New Brunswick, Fredericton NB, Canada.
Laura MiddletonDepartment of Kinesiology and Health Sciences, University of Waterloo, Ontario, Canada.
Lesley MillerCo-president of Citizen Advisory Group, Canada.
Haakon B NygaardDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Manuel Montero-OdassoLawson Health Research Institute, London, Ontario, Canada; Gait and Brain Lab, Parkwood Institute, University of Western Ontario, London, Ontario, Canada; Departments of Medicine and Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada.
Kelly MurphyDepartments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Natalie PhillipsDepartment of Psychology, Concordia University, Montréal, Québec, Canada.
M Kathleen Pichora-FullerDepartments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Julie M RobillardDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Eric E SmithHotchkiss Brain Institute, Calgary, Alberta, Canada; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Mark SpeechleyDepartment of Epidemiology & Biostatistics, Schulich Interfaculty Program in Public Health, Western University.
Amal TriguiCentre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada; Département de nutrition, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada.
Walter WittichÉcole d'optométrie, Université de Montréal, Montréal, Québec, Canada.
Howard ChertkowRotman Research Institute, Baycrest Academy for Research & Education, Toronto, Ontario, Canada; Lady Davis Institute for Medical Research, Montréal, Québec, Canada; Department of Medicine (Neurology), University of Toronto, Toronto, Ontario, Canada; Department of Neurology and Neurosurgery, McGill University, Canada.
Howard H FeldmanDepartment of Neurosciences, University of California, San Diego, California, USA; Alzheimer's Disease Cooperative Study, School of Medicine, University of California. San Diego California USA.
CTU expert group for the Canadian Consortium on Neurodegeneration in Aging (CCNA), CAN-THUMBS UP Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnline educational programs focused on ways to improve brain health could increase participant literacy, empowerment, and engagement in activities that support personal brain health, potentially reducing dementia risk.

objectivesOur goal was to develop an evidence-based online educational program with a focus on risk and protective factors for dementia. Here we present the rationale and features of the program and include results from a pilot study that assessed usability and acceptability.

designThis project is part of the Can-Thumbs UP (CTU) initiative. An Intervention Mapping Approach framework and co-construction approach was used to develop the online program. A pre-post pilot open label design was used to test the usability and acceptance of this at-home educational program.

settingThe program and assessment for the pilot study were delivered fully remotely.

participantsTwenty community-dwelling older adults (60-83 years of age, 65 % female) living in Canada who were at increased risk of dementia. PROGRAM: The Brain Health PRO/Santé Cerveau PRO is a web-based 45-week program available in French and English. It provides general information and guidance on seven modifiable risk factors for dementia: physical activity, nutrition, cognitively stimulating activities, sleep, social and psychological health, vascular health, and vision/hearing. After completing a brief intake questionnaire, users are provided with an individualized risk profile to personalize priorities and goals. During the course of the program, users receive feedback on lifestyle changes. For this pilot study, participants completed a 15-week version of the program. MEASUREMENTS: This pilot study reports measures of usability (System Usability Scale), acceptance (Technology Acceptance Model-2) as well as risk profiles at intake based on self-reported questionnaires.

resultsTwo logic models were developed to identify the determinants of risk for dementia and how these could be targeted by the program. A review of dementia risk and protective factors and online educational programs for older adults, as well as co-creation activities with experts, stakeholders, and citizen advisors, were used to identify the determinants, target, format, and content of the program. The pilot study reports excellent usability and acceptance with scores of 80.4/100 and 93.5/120 respectively.

conclusionIntervention mapping and co-construction approaches facilitated the design of a program that effectively balances the delivery of scientific content with the specific constraints, needs and abilities of older adults.

trial registrationNCT05347966.

Indexed as

DementiaHealth LiteracyInternetRisk Reduction BehaviorAgedAged, 80 and overCanadaFemaleHumansMaleMiddle AgedPilot ProjectsRisk FactorsAlzheimer's diseasecomputer assisted trainingmodifiable risk factorsmultidomain interventionsprevention

Identifiers

PMID40090784
PMCPMC12434268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.