Evidence map›Paper›PMID 40089863›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis.

Tianjiao Deng, Xinyi Jing, Liuqi Shao, Yakun Wang, Congrui Fu, Hongxiao Yu, Xiaoyi Wang, Xue Zhao, Fanrao Kong, Yake Ji and 7 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Article
  8. Article
  9. A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tianjiao DengDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Xinyi JingDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Liuqi ShaoDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Yakun WangDepartment of Sleep Medicine, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Congrui FuNursing School, Hebei Medical University, Shijiazhuang, 050031, China.
Hongxiao YuDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Xiaoyi WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Xue ZhaoDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Fanrao KongDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Yake JiDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Xiaochen TianDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Wei HeDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Shangyu BiDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Luo ShiDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Hanqiao WangDepartment of Sleep Medicine, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Fang YuanDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.
Sheng WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.ORCID https://orcid.org/0000-0001-9579-4808

Funding

Hebei Medical University Natural Science Foundation YBKJ202403Hebei Province Yanzhao Golden Platform Project HJZD202510Natural Science Foundation of China 31971058Natural Science Foundation of China 82000001Natural Science Foundation of China 82200108Natural Science Foundation of China U23A20431Natural Science Foundation of Hebei Province for Innovative Research Group Project H2021206203
6 · The paper itself

Abstract

The dynamic interaction between central respiratory chemoreceptors and the respiratory central pattern generator constitutes a critical homeostatic axis for stabilizing breathing rhythm and pattern, yet its circuit-level organization remains poorly characterized. Here, the functional connectivity between two key medullary hubs: the nucleus tractus solitarius (NTS) and the preBötzinger complex (preBötC) are systematically investigated. These findings delineate a medullary network primarily comprising Phox2b-expressing NTS neurons (NTS

Indexed as

HomeostasisMedulla OblongataRespirationSolitary NucleusAnimalsMaleMiceMice, Inbred C57BLNeuronsRespiratory Centerbreathing patterncentral respiratory chemoreceptornucleus tractus solitariusPhox2bTRPC5

Identifiers

PMID40089863
PMCPMC12079440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.