Evidence map›Paper›PMID 40089794›Full record

ArticleBMC oral health2025

Comparative evaluation of chlorhexidine and benzalkonium chloride pretreatments on bond strength durability of immediate dentin sealing with universal adhesive: an in vitro study.

Fereshteh Shafiei, Zahra Jowkar, Sepideh Eslamipanah, Mahshid Mohammadi-Bassir, Maryam Doozandeh, Mahsa Kowkabi

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fereshteh ShafieiOral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra JowkarOral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. zahrajowkar66@gmail.com.ORCID http://orcid.org/0000-0003-4447-3670
Sepideh EslamipanahDepartment of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahshid Mohammadi-BassirDepartment of Operative Dentistry, School of Dentistry, Shahed University, Tehran, Iran.
Maryam DoozandehDepartment of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahsa KowkabiDepartment of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

Shiraz University of Medical Sciences 11447
6 · The paper itself

Abstract

backgroundEffective and durable bonding of immediate dentin sealing (IDS) is a crucial factor in the success of adhesive-bonded restorations. This study aimed to investigate the influence of chlorhexidine (CHX) and benzalkonium chloride (BAC) pretreatments on the immediate and aged bond strengths of a universal adhesive used in IDS across two etching modes.

methodsFlat dentin surfaces were obtained from 120 molars and divided into six groups based on pretreatments (no treatment, CHX, and BAC) in two etching modes (etch-and-rinse (E&R) and self-etch (SE)) using All Bond Universal, in conjunction with a hydrophobic resin layer. Following the provisional stage and resin cementation, immediate and aged shear bond strengths (SBS) were measured after 24 h and 1 year of storage, respectively. The data (in MPa) were analyzed using ANOVA and Tukey tests (p < 0.05).

resultsCHX pretreatment did not significantly impact bond strengths, while BAC pretreatment led to a significantly lower immediate SBS in the SE mode (9.91 ± 1.93 MPa) compared to the control group (16.07 ± 3.45 MPa, p < 0.001). In the E&R mode, no statistically significant differences were found among the three pretreatment groups at either storage time (p > 0.05). After one year, SBS values in the SE mode decreased for all groups, with the CHX group showing the lowest value (9.98 ± 3.91 MPa), though these reductions were not statistically significant (p > 0.05). In contrast, SBS values in the E&R mode remained stable or slightly increased, with the BAC group reaching 17.12 ± 4.05 MPa after one year. Aged SBS values in the E&R mode were significantly higher than in the SE mode for the CHX (16.53 ± 2.28 MPa vs. 9.98 ± 3.91 MPa, p < 0.001) and BAC groups (17.12 ± 4.05 MPa vs. 10.55 ± 3.03 MPa, p = 0.001).

conclusionCHX and BAC pretreatments did not offer additional advantages in terms of long-term bonding performance in IDS with the universal adhesive utilized in this study. When using antibacterial agents, All Bond Universal adhesive in E&R mode could provide better long-term bonding performance than that of its SE mode.

Indexed as

Anti-Infective Agents, LocalBenzalkonium CompoundsChlorhexidineDental BondingDentinDentin-Bonding AgentsAcid Etching, DentalDental Stress AnalysisHumansIn Vitro TechniquesMaterials TestingResin CementsShear StrengthTime FactorsAnti-Infective Agents, LocalBenzalkonium CompoundsChlorhexidineDentin-Bonding AgentsResin CementsBenzalkonium chlorideBond strengthChlorhexidineImmediate dentin sealing

Identifiers

PMID40089794
PMCPMC11909887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.