Evidence map›Paper›PMID 40089785›Full record

ReviewBiotechnology for biofuels and bioproducts2025

Bacillus subtilis surface display technology: applications in bioprocessing and sustainable manufacturing.

Howra Bahrulolum, Gholamreza Ahmadian

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels and bioproducts, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. RecombinantFrontiers in immunology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Howra BahrulolumDepartment of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Gholamreza AhmadianDepartment of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. ahmadian@nigeb.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing demand for sustainable and eco-friendly alternatives in bioprocessing, healthcare, and manufacturing has stimulated significant interest in Bacillus subtilis surface display technology. This innovative platform, leveraging both spore and vegetative cell forms, provides exceptional versatility for a wide spectrum of applications, spanning from green technologies to advanced biomedical innovations. The robustness of spores and the metabolic activity of vegetative cells enable efficient enzyme immobilization, biocatalysis, and biosensor development, facilitating bioremediation, pollutant degradation, and renewable energy generation. Additionally, B. subtilis surface display systems have demonstrated remarkable potential in vaccine development and drug delivery, offering a cost-effective, scalable, and environmentally sustainable alternative to traditional methods. These systems can effectively present antigens or therapeutic molecules, enabling targeted drug delivery and robust immune responses. This review explores recent advancements, challenges, and opportunities in harnessing B. subtilis surface display technology for sustainable biomanufacturing, green innovations, and transformative biomedical applications, emphasizing its role in addressing pressing global challenges in environmental sustainability and healthcare.

Indexed as

Bacillus subtilisEnvironmental biotechnologySurface display technologySustainable biomanufacturingVaccine development

Identifiers

PMID40089785
PMCPMC11909954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.