Evidence map›Paper›PMID 40089582›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Sequential direct bilirubin values in preterm infants.

Abigail McCay, Odinaka Onuigbo, MaCee Boyle, Sahla Esam, Shreya Gaddipati, Charles B Chen, Sanu Yadav, Akshaya Vachharajani

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abigail McCayUniversity of Missouri School of Medicine, Columbia, MO, USA. amnzy@umsystem.edu.ORCID http://orcid.org/0009-0009-6986-4409
Odinaka OnuigboUniversity of Missouri School of Medicine, Columbia, MO, USA.
MaCee BoyleUniversity of Missouri School of Medicine, Columbia, MO, USA.
Sahla EsamUniversity of Missouri School of Medicine, Columbia, MO, USA.
Shreya GaddipatiUniversity of Missouri School of Medicine, Columbia, MO, USA.
Charles B ChenUniversity of Missouri School of Medicine, Columbia, MO, USA.
Sanu YadavUniversity of Missouri School of Medicine, Columbia, MO, USA.
Akshaya VachharajaniUniversity of Missouri School of Medicine, Columbia, MO, USA.ORCID http://orcid.org/0000-0002-0729-1790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aim to describe sequential direct bilirubin levels in preterm infants and examine the outcomes of subsequent evaluation of direct hyperbilirubinemia. STUDY

designRetrospective electronic chart analysis of preterm infants admitted and surviving the neonatal intensive care unit (NICU) stay was performed.

resultA total of 127 preterm infants had 665 bilirubin measurements (333 direct bilirubin; 332 total bilirubin) during their first NICU stay. Before five days of age, twenty-seven (27/127, 21%) infants had abnormal direct bilirubin estimations. At fourteen days, three of these infants (3/27, 11%) had abnormal values. All three infants had further testing and more direct bilirubin estimations than their cohort. All infants had normal levels by discharge. Age-appropriate direct bilirubin values were based on those described by Feldman et al.

conclusionAll preterm infants with elevated direct bilirubin had normal values by discharge.

Indexed as

BilirubinHyperbilirubinemia, NeonatalInfant, PrematureFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalMaleRetrospective StudiesBilirubin

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.