Evidence map›Paper›PMID 40089569›Full record

Trial reportInternational journal of obesity (2005)2025

Five-year follow-up of a randomized weight loss trial on a digital health behaviour change support system.

Eero Turkkila, Taru Pekkala, Heta Merikallio, Marko Merikukka, Laura Heikkilä, Janne Hukkanen, Harri Oinas-Kukkonen, Tuire Salonurmi, Anna-Maria Teeriniemi, Terhi Jokelainen and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eero Turkkila *Research Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0009-0002-4705-9707
Taru Pekkala *Research Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0009-0009-3418-5254
Heta MerikallioResearch Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland. heta.merikallio@oulu.fi.ORCID 0000-0002-0967-3987
Marko MerikukkaResearch Service Unit, Oulu University Hospital, Oulu, Finland.
Laura HeikkiläResearch Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0002-5621-7212
Janne HukkanenResearch Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0003-4981-0525
Harri Oinas-KukkonenOulu Advanced Research on Service and Information Systems, University of Oulu, Oulu, Finland.ORCID 0000-0002-1442-0562
Tuire SalonurmiResearch Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0001-5104-5792
Anna-Maria TeeriniemiMedical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.
Terhi JokelainenPsychiatry, University of Oulu and Oulu University Hospital, Oulu, Finland.
Markku J SavolainenResearch Unit of Biomedicine and Internal Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0002-2557-6423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe weight regain after successful weight loss is a common challenge. This study aimed to assess the long-term effectiveness of a web-based health behaviour change support system (HBCSS) utilizing persuasive systems design (PSD) and methods of cognitive behavioural therapy (CBT). We have previously demonstrated the two-year effectiveness of the HBCSS.

methodsIn total, 532 participants with overweight or obesity (BMI 27-35 kg m

resultsMean weight change (%) (95% CI) from baseline among HBCSS and non-HBCSS users was 1.5 (-0.02 to 2.9), p = 0.056 and 1.9 (0.3-3.3), p = 0.005, respectively, at five years. Of the six groups, the SHG group without HBCSS had a statistically significant increase in weight (%) from baseline at five years (3.1, 95% CI 0.6 to 5.6, p = 0.010). The other groups did not have a significant increase in weight. There was no significant difference between groups at five years in weight. Fewer blood pressure medications were started over the five-year period in HBCSS group (p = 0.046).

conclusionThe 12-month HBCSS intervention was not able to maintain reduced weight better than non-HBCSS at 5 years. However, there were significant weight difference favouring HBCSS over the whole 5-year period. The decrease in the need for antihypertensives suggests that the significant weight loss by HBCSS at early years has a health-promoting legacy effect.

Indexed as

Health BehaviorObesityWeight LossWeight Reduction ProgramsAdultCognitive Behavioral TherapyDigital HealthFemaleFollow-Up StudiesHumansMaleMiddle AgedOverweight

Identifiers

PMID40089569
PMCPMC12095081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.