EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity.
Ran Jing, Irene Scarfo, Mohamad Ali Najia, Edroaldo Lummertz da Rocha, Areum Han, Michael Sanborn, Trevor Bingham, Caroline Kubaczka, Deepak K Jha, Marcelo Falchetti and 4 more
Article in Cell stem cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Customized stem cells for clinical application in blood disordersR24DK092760 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI COLLINS, JAMES J, DALEY, GEORGE Q · 2011 to 2018
$10.7M
Human Pluripotent Stem Cell and Progenitor Models of Cardiac and Blood DiseasesU01HL100001 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI DALEY, GEORGE Q, ORKIN, STUART H · 2009 to 2015
$8.9M
Molecular Circuits in the Hematopoietic Stem Cell NicheRC2DK120535 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI COLLINS, JAMES J, DALEY, GEORGE Q · 2020 to 2024
$8.2M
Humanized Mouse Avatars for T1DU01DK104218 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BREHM, MICHAEL ALLEN, GREINER, DALE LESLIE · 2019 to 2023
$4.5M
Humanized Mouse Avatars for T1DUC4DK104218 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BREHM, MICHAEL ALLEN, DALEY, GEORGE Q · 2014 to 2014
$4.1M
Novel therapies for Fanconi anemiaRC4DK090913 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI D'ANDREA, ALAN D., DALEY, GEORGE Q · 2010 to 2010
$3.9M
Murine Models for Regenerative MedicineR01DK070055 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI DALEY, GEORGE Q · 2005 to 2009
$3.5M
Comparative phenotypic, functional, and molecular analysis of ESC and iPSCRC2HL102815 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI CHURCH, GEORGE M, COLLINS, JAMES J · 2009 to 2010
$3.4M
Developmental Activation of the Inflammasome Controls Hematopoietic Stem Cell ProductionR01HL154580 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI NORTH, TRISTA E. · 2020 to 2023
$2.2M
Understanding the role of the lin28 paralogs and branching morphogenesisR01GM107536 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI DALEY, GEORGE Q · 2014 to 2017
$1.9M
Modeling Developmental Hematopoiesis with Embryonic StemR01HL071265 · NHLBI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI DALEY, GEORGE Q · 2002 to 2005
$971k
Second International Conference on Stem Cell EngineeringR13HL104873 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI DALEY, GEORGE Q · 2010 to 2010
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity. · full record | OpenQuestion