Evidence map›Paper›PMID 40088382›Full record

ArticleLasers in medical science2025

The effectiveness of nitrogen plasma skin rejuvenation in the treatment of acne vulgaris in Asians.

Kento Takaya, Kazuo Kishi

Abstract read
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Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kento TakayaDepartment of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan. kentotakaya@keio.jp.
Kazuo KishiDepartment of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports on the use of plasma skin regeneration for the treatment of acne vulgaris are limited. We aimed to report on the effectiveness of nitrogen PSR in the treatment of acne vulgaris. Participants with acne vulgaris were enrolled and underwent three consecutive PSR sessions at 4-week intervals. Facial surface analysis was performed as an evaluation of treatment efficacy through objective computerized evaluation using the Canfield VISIA imaging system. Post-treatment subjective evaluations were performed and analyzed using the Clinical Global Impression Improvement Scale (CGI-I) and the Patient Global Impression Improvement Scale (PGI-I). Pain levels and other complications were recorded at each follow-up visit. At 2 months after the final treatment, the patients' subjective evaluation of the treatment was obtained. Twenty patients were included in the analysis. There was a significant improvement in the porphyrin VISIA System score and in the erythematous area. Additionally, the fine lines, pores, and skin texture showed significant improvements after three sessions, and both the mean CGI-I and PGI-I scores improved significantly. Two patients experienced temporary acne worsening; however, no other side effects were observed. All patients were satisfied with the treatment and did not report any significant adverse effects on their lifestyle. Nitrogen PSR is an effective and safe treatment for inflammatory acne, with minimal recovery time and no significant complications.

Indexed as

Acne VulgarisNitrogenPlasma Skin RegenerationRejuvenationAdultAsian PeopleFemaleHumansMalePatient SatisfactionTreatment OutcomeYoung AdultNitrogenAcne vulgarisCutibacterium acnesInflammatory acnePlasma skin rejuvenation

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.