Evidence map›Paper›PMID 40088368›Full record

ArticleJournal of materials science. Materials in medicine2025

Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus.

Amir Elhadad, Tayebeh Basiri, Ashwaq Al-Hashedi, Sophia Smith, Hanan Moussa, Sadiya Veettil, Eva Mª Pérez Soriano, Faleh Tamimi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amir ElhadadDepartment of Pre-Clinical Oral Health Sciences, College of Dental Medicine, QU-Health, Qatar University, Doha, Qatar.
Tayebeh BasiriFaculty of Dentistry, McGill University, Montreal, QC, Canada.
Ashwaq Al-HashediFaculty of Dentistry, McGill University, Montreal, QC, Canada.
Sophia SmithDepartments of Material Engineering, McGill University, Montreal, QC, Canada.
Hanan MoussaDepartment of Applied Oral Sciences, Faculty of Dentistry, Dalhousie University, Halifax, NS, Canada.
Sadiya VeettilDepartment of Pre-Clinical Oral Health Sciences, College of Dental Medicine, QU-Health, Qatar University, Doha, Qatar.
Eva Mª Pérez SorianoEscuela Politécnica Superior, Universidad de Sevilla, Seville, Spain.
Faleh TamimiDepartment of Pre-Clinical Oral Health Sciences, College of Dental Medicine, QU-Health, Qatar University, Doha, Qatar. fmarino@qu.edu.qa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental calculus, a main contributor of periodontal diseases, is mostly composed of inorganic calcium phosphate species such as dicalcium phosphate, whitlockite, octa calcium phosphate, and hydroxyapatite. Under physiological pH 7.4, dicalcium phosphates can gradually interact with calcium carbonate to form hydroxyapatite. Therefore, we hypothesized that aragonite (Arg) could react with dental calculus, facilitating its removal. To assess the reactivity of Arg with dental calculus, we examined the changes in surface morphology, composition, and topography of Arg and dental calculus upon exposure to each other in an aqueous environment. The impact of Arg on the removal of dental calculus was assessed by brushing polished sections of dental calculus, enamel, and dentin with slurries of Arg and measuring the depth of abrasion using a stylus profilometer. Our results demonstrate that Arg can react with dental calculus in aqueous environment. This reaction increases calculus surface roughness which in turn facilitate dental calculus removal by brushing. Aragonite could be a promising abrasive for toothpaste design for management of dental calculus.

Indexed as

Calcium CarbonateCalcium PhosphatesDental CalculusDental EnamelDentinHumansSurface PropertiesToothpastesCalcium Carbonatecalcium phosphate, dibasic, dihydrateCalcium PhosphatesToothpastes

Identifiers

PMID40088368
PMCPMC11910395

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.